Modulating the gut microbiome to power radiation therapy in lung cancer

A team headed by Claude Perreault, Director of IRIC's Immunobiology Research Unit and Professor at the Faculty of Medicine at Université de Montréal, has identified novel tumor antigens that could lead to the development of vaccines for the treatment of two cancers: melanoma and non-small cell lung cancer.

Precision medicine promises to tailor health care to the individual. But what happens when entire communities are left out of the data that drives that tailoring?

A Henan University of Science and Technology team reports that boosting miR-542-3p thwarts stress-related cell loss in the hippocampus and eases depressive-like behavior in mice.

An Australian vaping education program being rolled out in schools nationally has been hailed as one of the most successful school-based strategies in the world for curbing youth e-cigarette use in a study published today in The Lancet Public Health.

A review published in Addiction looks at what interventions have been effective in changing the perception of how harmful vaping is, and how that may affect vaping and smoking behaviors.

Scientists in Ghent have achieved a breakthrough in sepsis research. In a study on mice, the researchers demonstrated that vitamin B1 (thiamine pyrophosphate, TPP) restores mitochondrial energy metabolism, drastically reduces lactate production, and increases survival rates in sepsis. The study results are published in Cell Reports.

Patients with post-traumatic stress disorder (PTSD) often struggle to forget traumatic memories, even long after the danger has passed. This failure to extinguish fear memories has long puzzled scientists and posed a major hurdle for treatment, especially since current medications targeting serotonin receptors offer limited relief for only a subset of patients.

Eight different vitamins make up the B complex, and they all play crucial roles in the body, such as producing energy, keeping our nervous system healthy, and supporting cell development. If eight sounds like a lot to keep track of, it might help to know that most research focuses on five in particular: thiamine (B1), riboflavin (B2), niacin (B3), folate (B9), and cobalamin (B12).

About 2.7 million people in the U.S. live with inflammatory bowel diseases, which cause long-term inflammation in the digestive system. The number of children diagnosed with these conditions, like Crohn's disease, is rising faster than in adults, but the reasons for the increase are puzzling.

Hospital for Sick Children in Toronto researchers are reporting that targeted RNA sequencing can detect clinically actionable alterations in 87% of tumors and provide decisive findings where DNA-seq either fails, returns no variant, or is not informative.

Findings from a study published in The Lancet Public Health provide the strongest evidence to date that salt warning labels on restaurant menus are perceived by consumers as effective in discouraging selection of high-salt items, prompt greater awareness of salt content when ordering, and significantly reduce the amount of salt actually ordered.

COVID-19 is once again on the rise in California.

Understanding how the human brain stores information and later uses it to complete various tasks has been a long-standing goal of neuroscience and psychology research. Past studies have identified different types of memory processes that have distinct roles and characteristics.

Regular exercise provides a wide range of benefits, including weight management, improved cardiovascular health and sleep quality. But for many people, common forms of exercise, such as walking, running and weight training, are a struggle due to pain, weakness, mobility issues or fear of falling.

Across the nation, Medicaid is the single largest payer for mental health care, and in rural America, residents disproportionately rely on the public insurance program.

New research from scientists at the Marshall University Joan C. Edwards School of Medicine reveals that certain gut microbial byproducts may hold promise as a novel therapy for obesity-associated metabolic complications by restoring critical hormone-producing cells in the intestine.

High levels of a hormone found in cells in the gut could underlie many cases of chronic diarrhea and help explain up to 40% of cases of patients with irritable bowel syndrome with diarrhea, according to a new study led by scientists at the University of Cambridge.

Urinary incontinence is a devastating condition affecting over 33 million Americans, according to the National Association for Continence, leading to significant adverse impacts on patients' mental health and quality of life. Disorders of urination are also a key feature of all neurological disorders.