Nerve pain drug gabapentin linked to increased dementia, cognitive impairment risks
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- 2025-07-11 05:30 event
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A new weekly injectable drug could transform the lives of more than eight million people living with Parkinson's disease, potentially replacing the need for multiple daily tablets.
Women diagnosed with premenstrual symptoms have a slightly increased risk of developing cardiovascular disease later in life. This is shown by a new study from Karolinska Institutet published in Nature Cardiovascular Research.
To simulate blood flow inside brain aneurysms, researchers from Japan have developed a computational method that combines 4D flow MRI, computational fluid dynamics, and data assimilation, which provides greater accuracy and efficiency. By focusing only on the aneurysm region, this approach significantly reduces computational cost while improving flow estimation. When validated on patient data, it outperforms conventional models—offering a practical tool for patient-specific risk assessment and treatment strategies.
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The involvement of children's social care services was a common factor in nearly a third of UK maternal deaths occurring during, or within a year of, pregnancy between 2014 and 2022, finds research published in BMJ Medicine.
Children from ethnic minority backgrounds and those living in areas with higher levels of child poverty were more likely to die in intensive care than white children and those from the least deprived areas.
Being consistently physically active in adulthood is linked to a 30–40% lower risk of death from any cause in later life, while upping levels from below those recommended for health is still associated with a 20–25% lower risk, finds a pooled data analysis of the available evidence, published online in the British Journal of Sports Medicine.
Receiving six or more prescriptions of the drug gabapentin for low back pain is associated with significantly increased risks of developing dementia and mild cognitive impairment (MCI)—29% and 85%, respectively—finds a large medical records study published online in the journal Regional Anesthesia & Pain Medicine.
It can be difficult to decide whether to expedite birth when a woman in the final stage of pregnancy perceives fewer fetal movements. An additional ultrasound measurement to assess resistance in fetal blood vessels can help make this decision more accurately, leading to fewer complications during delivery.
For younger acute myocardial infarction (AMI) survivors, living in marginalized neighborhoods is associated with adverse outcomes, according to a study published online July 2 in JAMA Network Open.
New research from the University of Sydney has found that children are at a similar risk of dehydration and hyperthermia in extreme heat as adults, contradicting previous advice that children are more susceptible to heat-related illnesses.
Scientists at The Wistar Institute have discovered that a class of FDA-approved cancer drugs known as PARP1 inhibitors can effectively combat Epstein-Barr virus (EBV)-driven lymphomas. The findings, published in the Journal of Medical Virology, demonstrate that these drugs, which work by blocking the activity of the PARP1 enzyme, can halt tumor growth by interfering with the EBV's ability to activate key cancer-promoting genes.
A research study establishes a strong correlation between distressed births and experiencing mental and physical problems later in life.
The skin has two types of adult stem cells: epidermal and hair follicle. Their jobs seem well-defined: maintaining the skin, or maintaining hair growth. But as research from Rockefeller University has shown, hair follicle stem cells (HFSCs) can switch teams, pitching in to heal the skin when it receives an injury. How do these cells know it's time to pivot?
Intermittent fasting is as effective as traditional calorie-restriction diets for weight loss, according to a new review of evidence led by University of Toronto researchers.
A new study conducted in Lake County, California—one of the most wildfire-affected regions in the country—has found that residents' anxiety and stress about climate change are associated with increased disaster-preparedness behaviors.
Four years after pre-surgery treatment with a novel combination of immune checkpoint inhibitors, nivolumab and relatlimab, 87% of patients with stage III melanoma remained alive, according to new results from a study led by researchers at The University of Texas MD Anderson Cancer Center.