Novel immunotherapy strategy shows promising long-term survival in certain advanced NSCLC patients

New research presented identifies interferon-induced transmembrane protein 3 (IFITM3) as a critical regulator of immunotherapy sensitivity in small cell lung cancer (SCLC), offering a promising new avenue for overcoming resistance to PD-1/PD-L1 checkpoint blockade.

A layer deep in the cerebral cortex, which is the innermost layer of the mammalian brain, has recently been found to play a role in the regulation of brain states associated with wakefulness and attention.

Henagliflozin, a popular drug prescribed for type 2 diabetes, has demonstrated potential anti-aging effects in a recent study published in Cell Reports Medicine.

For every motor skill you've ever learned, whether it's walking or watchmaking, there is a small ensemble of neurons in your brain that makes that movement happen. Our brains trigger these ensembles—what we sometimes call "muscle memories"—to get our bodies cooking, showering, typing, and every other voluntary thing we do.

A new analysis from the PALOMA-2 study shows that subcutaneous administration of amivantamab every four weeks (Q4W), in combination with daily oral lazertinib, yields a high objective response rate in patients with previously untreated EGFR-mutated advanced non-small cell lung cancer (NSCLC).

Unarmed Black civilians are three times more likely to be shot and killed by police officers than unarmed white civilians in the U.S. In tragic cases in recent years, unarmed Black men holding innocuous objects like a wallet, cell phone, or vape pen were killed by police officers because those objects were misidentified as weapons.

Women taking popular weight-loss medications during their reproductive years may be unaware of associated risks to pregnancy and unborn babies, warn Flinders University researchers.

As the COVID-19 pandemic wound down, so did the federal government's funding to states that allowed all Medicaid enrollees to keep their coverage even if they no longer would have been eligible otherwise.

A randomized Phase II trial from National Taiwan University Hospital reports early evidence that resecting the primary thoracic tumor following EGFR tyrosine kinase inhibitor (TKI) therapy may prolong disease control in patients with metastatic EGFR-mutated non-small cell lung cancer (NSCLC).

Results from the Female Asian Nonsmoker Screening Study (FANSS) highlight the potential value of low-dose CT (LDCT) screening for lung cancer among a growing but underserved population: Asian women with no history of smoking.

A large-scale survey conducted by Lung Cancer Europe (LuCE) has identified critical communication barriers that affect information access, understanding, and shared decision-making among lung cancer patients and caregivers across Europe.

A new study presented at the International Association for the Study of Lung Cancer 2025 World Conference on Lung Cancer (WCLC) demonstrates that monitoring circulating tumor DNA (ctDNA) can refine and personalize the use of consolidation immunotherapy in patients with limited-stage small cell lung cancer (LS-SCLC).

For families of children with severe epilepsy, controlling seizures is often just the beginning of their challenges. Even in cases where powerful medications can reduce seizures, many children continue to face difficulties with learning, behavior and sleep that can be just as disruptive to daily life.

A team of researchers from Michigan State University and community partners has conducted critical research to address gaps in treatment of substance use disorder in Michigan's St. Clair County and the city of Port Huron. This research, culminating in support resources, comes in time for September: National Alcohol and Drug Addiction Recovery Month.

9 September 2025, Cairo, Egypt – Each year, on 10 September, World Suicide Prevention Day (WSPD) – organized by the International Association for Suicide Prevention (IASP) and co-sponsored by WHO – focuses global attention on suicide prevention, uniting communities, organizations and governments with the shared belief that suicidal behaviour is a major public health problem, one that must be addressed through raising awareness and promoting open discourse on this taboo subject. Changing the Narrative on Suicide, the triennial theme for WSPD 2024–2026, aims to do just that, to inspire individuals, communities, organizations and governments to engage in open and honest discourse about suicide and suicidal behaviour. More than 720 000 people die from suicide every year. In 2021, suicide was the third leading cause of death among 15–29-year-olds, with 73% of suicides occurring in low- and middle-income countries. Since 2019, suicide rates in the Eastern Mediterranean Region have declined by 17%. For each suicide, there are an estimated 20 suicide attempts. Each life lost has profound social, emotional and economic consequences, deeply affecting families, friends, workplaces and communities. The stigma surrounding suicide often prevents individuals from seeking help in a timely manner on one hand and hindering the development of evidence-based health and social care policies and services on the other. Suicidal behaviour is influenced by a complex interplay of social, cultural, economic, biological, psychological and environmental factors. Mental health conditions, experiencing conflict, disaster, loss, discrimination, violence, abuse, relationship problems, chronic pain and illness and Read more...

A viewpoint article published in Brain Medicine. by Dr. Esther Sternberg provides a compelling portrait of how one pioneering neuroscientist continues to thrive beyond his centennial year.

Researchers have developed a material that can sense tiny changes within the body, such as during an arthritis flareup, and release drugs exactly where and when they are needed.

A large portion of the global population with diabetes remains undiagnosed or is not receiving optimal care, according to a new study published in The Lancet Diabetes & Endocrinology.