Popular diabetes drug shows anti-aging effects among patients with type 2 diabetes

Researchers identified almost two dozen previously unknown genetic variants linked to type 2 diabetes by including participants' hormone levels in their analysis. Yan V. Sun of Emory University, U.S., and colleagues report these findings in the open-access journal PLOS Genetics.

Preliminary findings from a new clinical trial show no adverse neurodevelopmental effects after brief inhaled anesthesia and surgery in infants and young children, reports Anesthesiology.

The University of Kentucky Markey Cancer Center's Graham Warren, M.D., Ph.D., and international collaborators have led a groundbreaking study that could change the way lung cancer is diagnosed and treated.

Implementing changes to indoor environments, such as cooler bedrooms at night and increasing the amount of bright light during the day, could significantly improve sleep for people living with dementia, according to a study led by the University of Surrey.

The acquisition of opioid treatment programs by private equity investors is a growing national trend, prompting questions about the potential to expand access to methadone, a medication that can cut the risk for overdose deaths by more than half. Opioid treatment programs are currently the only settings with the legal authority to dispense methadone for the treatment of opioid use disorders.

New research from University of Virginia psychologists has found that "epigenetic clocks"—tools scientists use to estimate a person's biological age—can predict cognitive decline. The study, which focused on middle-aged twins, also found socioeconomic status plays a role.

Yale School of Medicine-led research reports that nerve-associated macrophages help maintain healthy fat over a lifespan and curb age-related inflammation.

New research presented identifies interferon-induced transmembrane protein 3 (IFITM3) as a critical regulator of immunotherapy sensitivity in small cell lung cancer (SCLC), offering a promising new avenue for overcoming resistance to PD-1/PD-L1 checkpoint blockade.

A layer deep in the cerebral cortex, which is the innermost layer of the mammalian brain, has recently been found to play a role in the regulation of brain states associated with wakefulness and attention.

For every motor skill you've ever learned, whether it's walking or watchmaking, there is a small ensemble of neurons in your brain that makes that movement happen. Our brains trigger these ensembles—what we sometimes call "muscle memories"—to get our bodies cooking, showering, typing, and every other voluntary thing we do.

A new analysis from the PALOMA-2 study shows that subcutaneous administration of amivantamab every four weeks (Q4W), in combination with daily oral lazertinib, yields a high objective response rate in patients with previously untreated EGFR-mutated advanced non-small cell lung cancer (NSCLC).

Unarmed Black civilians are three times more likely to be shot and killed by police officers than unarmed white civilians in the U.S. In tragic cases in recent years, unarmed Black men holding innocuous objects like a wallet, cell phone, or vape pen were killed by police officers because those objects were misidentified as weapons.

Women taking popular weight-loss medications during their reproductive years may be unaware of associated risks to pregnancy and unborn babies, warn Flinders University researchers.

As the COVID-19 pandemic wound down, so did the federal government's funding to states that allowed all Medicaid enrollees to keep their coverage even if they no longer would have been eligible otherwise.

A randomized Phase II trial from National Taiwan University Hospital reports early evidence that resecting the primary thoracic tumor following EGFR tyrosine kinase inhibitor (TKI) therapy may prolong disease control in patients with metastatic EGFR-mutated non-small cell lung cancer (NSCLC).

A new study presented reports encouraging long-term survival outcomes from an experimental viral immunotherapy, CAN-2409, in patients with advanced non-small cell lung cancer (NSCLC) who previously failed to respond adequately to immune checkpoint inhibitors (ICI).

Results from the Female Asian Nonsmoker Screening Study (FANSS) highlight the potential value of low-dose CT (LDCT) screening for lung cancer among a growing but underserved population: Asian women with no history of smoking.

A large-scale survey conducted by Lung Cancer Europe (LuCE) has identified critical communication barriers that affect information access, understanding, and shared decision-making among lung cancer patients and caregivers across Europe.