People with sensitive personalities more likely to experience mental health problems, analysis indicates

The off-label use of ketamine to treat chronic pain is not supported by scientific evidence, a new Cochrane review has found.

A COVID infection, particularly in women, may lead to blood vessels aging around five years, according to research published in the European Heart Journal.

Ann Johnson became paralyzed after a brainstem stroke at age 30. As a participant in a clinical trial led by researchers at UC Berkeley and UC San Francisco, she finally heard her voice again.

A global mental health crisis is evolving. And at the forefront of the surging rates of mental health disorders globally are women, who are disproportionately affected when compared to men.

One of the world's most dangerous water-borne microorganisms, commonly called a "brain-eating amoeba," has recently been detected in two drinking water supplies in southwest Queensland.

When you order a coffee, do you ask for it to be "extra hot?"

A narrow majority of Americans now believe even moderate consumption of alcohol negatively affects health, as US drinking levels continue to decline, according to a recent survey.

Researchers from Children's Hospital of Philadelphia (CHOP) and Children's Hospital Colorado have found that better control of chronic eosinophilic esophagitis (EoE)-associated inflammation during childhood leads to less stiffening of the esophagus, resulting in fewer disease complications. Using Endoluminal functional imaging (FLIP), the study team suggests this could be a key marker for assessing disease severity and progression. The findings were published online today by the journal Gastroenterology.

One of the biggest challenges in cancer treatment is that certain cancers reappear after chemotherapy—and an aggressive type of blood cancer called acute myeloid leukemia (AML) is notorious for this. Now, new research from The Jackson Laboratory (JAX) points to a previously unknown molecular mechanism behind that chemoresistance, and a way to potentially disarm it.

High metabolic syndrome (MetS) severity, expressed by the continuous metabolic syndrome severity score (cMetS-S), is associated with development of chronic kidney disease (CKD), according to a study recently published in Kidney Diseases.

A considerable proportion of patients with high-grade serous cancer (HGSC) have missed opportunities for risk assessment with genetic testing and for surgical prevention, according to a study published online August 13 in JAMA Surgery.

New research presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15–19 September) shows that early detection of individuals at risk of diabetes is possible by analyzing the electronic records of people living within the same household for risk factors.

For children with monosymptomatic nocturnal enuresis (MNE), sleep fragmentation is negatively associated with physical and social quality of life, with N2 stage moderating the deleterious effects of fragmentation, according to a study published online May 13 in the International Journal of Environmental Research and Public Health.

Researchers have discovered eight new genes associated with schizophrenia, in the largest exome-sequencing study of the disorder ever conducted. The breakthrough, made by scientists at the Centre for Neuropsychiatric Genetics and Genomics (CNGG) at Cardiff University, provides new information and improves the understanding and future treatment development for schizophrenia.

When you see something—a tree in your backyard, say, or the toy your toddler hands you—that visual information travels from your retinas to your brain. And like a train stopping at stations along its route, the information pauses at particular regions of the brain where it's processed and sent along to its next location.

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma tumors but not in normal brain tissues. Preclinical research indicates that these missing RNA fragments can make difficult-to-treat tumors more responsive to immunotherapy. The findings were recently published in the journal Cell Reports.

A review published in the journal JAMA highlights innovative strategies to slow the biological aging process, an emerging approach with significant potential to prevent or delay multiple chronic diseases at once, one of the most pressing challenges in modern medicine today.

When bones break and there is extreme tissue loss—such as after a car accident or a battlefield injury—current treatments don't often lead to effective healing. But certain stem cells from skeletal muscles can improve recovery by producing all the types of cells needed to heal bones, according to a study co-led by scientists at the Perelman School of Medicine at the University of Pennsylvania and published in the Proceedings of the National Academy of Sciences.