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Proteins important in brain communication have different roles than previously thought

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  • 2025-07-02 03:02 event
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Proteins important in brain communication have different roles than previously thought
Cellular communication between neurons within our brain is complex and busy, much like a USPS mailroom.

1.981. Resilience and perceived gains can shape mental health in dementia caregivers

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University of Tennessee assistant professor Dr. Fei Wang's latest research, published in Research on Aging, uncovers how resilience plays a key role in shaping mental health outcomes among U.S. caregivers—especially distinguishing between those caring for individuals with dementia vs. non-dementia. The study also highlights how perceived gains from caregiving can enhance caregiver well-being.

1.982. Degree of weight loss affects tirzepatide-linked cardiometabolic risk improvement: Study

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For adults with obesity or overweight, tirzepatide-linked improvements in cardiometabolic risk factors are associated with the degree of weight reduction, according to a study published online June 24 in the Annals of Internal Medicine.

1.983. Menstrual cycle phases may be linked to higher alcohol craving and drinking

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Fluctuations in ovarian sex hormones across the menstrual cycle may influence women's likelihood of alcohol consumption, according to a study presented at the annual scientific meeting of the Research Society on Alcohol, held June 21 to 25 in New Orleans.

1.984. Self determination theory: How to use it to boost well-being

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Self-determination theory (SDT) is one of the most well established and powerful approaches to well-being in psychological research literature. Yet it doesn't seem to have broken through into popular discussions about well-being, happiness and self-help. That's a shame, because it has so much to contribute.

1.985. Breast cancer incidence trends vary by age

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Breast cancer incidence trends differ by age, even among older women, particularly by race and ethnicity and stage at diagnosis, according to a study published online June 24 in JAMA Network Open.

1.986. Gene signature of hepatic ferroptosis reveals its pathogenic features

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By establishing an iron overload-induced hepatic ferroptosis model, scientists from Japan have identified iFerroptosis—an integrated gene signature for ferroptosis. They evaluated the associated genes in both mice and human liver injury systems, validating the potential use of iFerroptosis as a biomarker. By highlighting the role of ferroptosis in liver injuries, this study offers insights into unique therapeutic targets.

1.987. An AI-based classification system for facial pigmented lesions

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A research team has developed a diagnostic system that uses artificial intelligence (AI) to accurately identify the type of facial pigmented lesions and support laser treatment decisions. A paper on this study was published online in Cureus.

1.988. Engineers create first immunocompetent leukemia device for CAR T immunotherapy screening

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A team of researchers led by NYU Tandon School of Engineering's Weiqiang Chen has developed a miniature device that could transform how blood cancer treatments are tested and tailored for patients.

1.989. Improvements to patient recovery strategies lower long-term opioid usage after colorectal surgery

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Minimizing opioid exposure during and after colorectal surgery can decrease long-term opioid use in some patients, according to new research by Mass General Brigham investigators.

1.990. Proteins important in brain communication have different roles than previously thought

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Cellular communication between neurons within our brain is complex and busy, much like a USPS mailroom.

1.991. Hidden bias may leave women and older adults underdiagnosed for HIV in Spain

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A recent study analyzes the extent to which HIV tests are conducted following the diagnosis of an HIV indicator condition (IC) in primary care, as recommended by the World Health Organization and the European Centre for Disease Prevention and Control. The article "Implicit bias in HIV testing based on indicator conditions in primary care: a population-based study in Catalonia, Spain, 2017 to 2021" was published in Eurosurveillance and led by researchers from the IGTP's research group Centre for Epidemiological Studies on HIV/AIDS and STI of Catalonia (CEEISCAT) and IDIAPJGol.

1.992. PHOx: An innovative, safer polymer for implantable medical devices

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A scientific team from the University of Liège has just developed an innovative polymer, PHOx, which could significantly improve the safety of implantable medical devices, while being more environmentally friendly. This invention is the subject of an international patent application.

1.993. Understanding the role of pigmentation in hereditary hearing loss

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Melanin can either protect or worsen hereditary hearing loss depending on genetic context, as reported by researchers from Japan. Using genetically engineered mice lacking the SLC26A4 gene, the researchers found that problems with melanin degradation led to its pathological accumulation in the inner ear, causing chronic inflammation and macrophage activation. These findings could inform new therapeutic strategies to minimize some forms of hereditary hearing loss.

1.994. Australian life expectancy inequality narrows, but disadvantaged areas still lag behind

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Australia has made progress in reducing socioeconomic inequalities in life expectancy since the late 2010s, according to new research from The Australian National University (ANU), setting the country apart from many other high-income countries.

1.995. Multiscale simulations successfully connect micro- and macro levels of brain activity

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Predicting how molecular changes affect the brain's overall activity is a major challenge in neuroscience. Many deep questions about the brain can only be understood by looking at several layers of brain activity at the same time—with a so-called "multi-scale" approach. For a long time, this had been considered out of reach.

1.996. Keeping brain-dead pregnant women on life support raises ethical issues that go beyond abortion politics

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Adriana Smith, a 30-year-old woman from Georgia who had been declared brain-dead in February 2025, spent 16 weeks on life support while doctors worked to keep her body functioning well enough to support her developing fetus. On June 13, 2025, her premature baby, named Chance, was born via cesarean section at 25 weeks.

1.997. Trump administration may cut funds to hospitals offering gender care to kids

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The Trump administration may cut off federal funding to hospitals that provide gender-related treatments to children and teens.

1.998. Conflicts of interest must be tackled to protect public health, argue researchers

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A new peer‐reviewed article by academics at the University of Bath warns that unless governments take urgent steps to address conflicts of interest with harmful industries—including tobacco, alcohol, ultra‐processed food, gambling and fossil fuels—efforts to prevent disease and protect public health will fail.

1.999. Ozempic-like drug significantly reduces frequency of chronic migraines in pilot study

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Migraines are a common ailment worldwide, affecting nearly 15% of the global population. At times, they can be debilitating enough to interfere with daily activities. Despite a multitude of treatment options, some migraine sufferers cannot find relief in available drugs. Others experience side effects that prevent the use of certain available migraine medications.

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