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Q&A: Are mitochondria the key to a healthy brain?

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  • 2025-07-02 19:58 event
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Q&A: Are mitochondria the key to a healthy brain?
Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was trying to record electrical currents inside the neurons of squids.

1.823. Nearly 1 in 6 older adults take aspirin despite no history of heart disease

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Around 1 in 6 older adults take aspirin as their primary method of preventing cardiovascular disease—despite stricter guidelines that no longer always call for it, a study finds.

1.824. Forecasting how abortion bans affect maternal mortality and morbidity

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Three years ago, the U.S. Supreme Court struck down the constitutional right to abortion care established by Roe v. Wade in 1973, leaving abortion access decisions to the states. To date, 13 states have a complete abortion ban and seven ban abortion at or before 18 weeks' gestation.

1.825. Benzaldehyde blocks pancreatic cancer spread by disrupting key protein interactions

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Cancer cells have the capacity to multiply rapidly. The aggressive cancer cells undergo conversion from their tightly connected epithelial state into a mesenchymal state, which lacks contact restrictions and spreads easily to other parts of the body. Such epithelial-to-mesenchymal plasticity also makes the cancer cells resistant to elimination by anticancer therapies.

1.826. Peer influence drives youth vaping epidemic, researchers find

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Young people with friends who vape are 15 times more likely to use e-cigarettes, and more adolescents are turning to illicit cannabis products, University of Queensland research has found.

1.827. Substance use implicated in most adult bath-related drownings

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Substance use was implicated in more than half of all adult drownings in baths or hot tubs in the last 10 years, according to an Australian-first study published in Drug and Alcohol Review.

1.828. Lab-grown 'tiny hearts' bring hope for children and adults with genetic heart disease

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Scientists from QIMR Berghofer's Cardiac Bioengineering Lab have developed lab-grown, three-dimensional heart tissues known as cardiac organoids that mimic the structure and function of real adult human heart muscle.

1.829. EEG recording during ambulance transport is possible even during long distance rides

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A joint study has evaluated the usability of a compact EEG device (BrainStatus) developed by Bittium Biosignals from Oulu during ambulance transports. The research was conducted by the Imaging center and Neurocenter of Kuopio University Hospital, the emergency medical services of the Wellbeing Services County of North Savo, and the University of Eastern Finland. The findings are published in the journal PLOS One.

1.830. Rare lung cells trigger rapid repair after smoke or virus exposure in mice—a similar pathway may exist in humans

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A rare cell in the lining of lungs is fundamental to the organ-wide response necessary to repair damage from toxins like those in wildfire smoke or respiratory viruses, Stanford Medicine researchers and their colleagues have found. A similar process occurs in the pancreas, where the cells, called neuroendocrine cells, initiate a biological cascade that protects insulin-producing pancreatic islet cells from damage.

1.831. Gut microbes and tryptophan enhance immunotherapy for difficult-to-treat brain tumors

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Advanced treatments, known as immunotherapies that activate T cells—our body's immune cells—to eliminate cancer cells, have shown limited efficacy as standalone therapies for glioblastoma, the most lethal form of brain tumor. This is due to their minimal response to glioblastoma and high resistance to treatment.

1.832. Q&A: Are mitochondria the key to a healthy brain?

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Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was trying to record electrical currents inside the neurons of squids.

1.833. Fluoride has greater benefits for vulnerable children

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Water fluoridation is effective in preventing tooth decay overall, but there are greater benefits for children from lower socioeconomic backgrounds, University of Queensland research has found.

1.834. Psilocybin rewires brain circuits to boost fear extinction and behavioral flexibility in mice

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Psilocybin, a psychedelic compound contained in some varieties of mushrooms, has recently been found to be promising for the treatment of some neuropsychiatric disorders, including depression, some anxiety disorders and post-traumatic stress disorder(PTSD). Some studies suggest that the consumption of this compound may be particularly advantageous for individuals who struggle to adapt their behavior in helpful ways when facing unexpected events or changes in their environment.

1.835. University steps up search for disease-spreading threats

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The University of Minnesota is stepping up efforts to identify biological threats that could trigger an epidemic, launching an institute to track disease-spreading infectious pathogens at the genetic level and monitor wastewater statewide.

1.836. Mimicking the benefits of exercise with a single molecule

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Capital Medical University, in collaboration with the Chinese Academy of Sciences, reports that betaine, a molecule produced in the kidney and enhanced through sustained exercise, operates as a potent inhibitor of inflammatory and aging-related pathways.

1.837. New research demonstrates accelerated cognitive gains in active service members

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As part of its ongoing quest to redefine how people understand and address the brain's health and performance, the Center for BrainHealth at UT Dallas collaborated with the Camp Pendleton Intrepid Center on new research investigating the effects of cognitive rehabilitation protocols on the brain performance of active-duty service members (ADSMs) with mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD). Cognitive strength, resilience, agility and focus are essential to military readiness and overall well-being.

1.838. Gun suicides in US reached record high in 2023

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More people in the United States died by gun suicide in 2023 than any year on record—more than by gun homicide, accidental shootings and police shootings combined.

1.839. How a multiple sclerosis drug reshapes the immune system

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When ocrelizumab became the first FDA-approved treatment for early forms of multiple sclerosis (MS) in 2017, it offered patients immense hope. The long-awaited drug is a monoclonal antibody that depletes B cells—the immune cells that drive MS progression. Exactly how ocrelizumab does this, however, remains unclear.

1.840. Endometriosis linked to four-times higher pregnancy rates than other causes of infertility, study reveals

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A landmark 30-year study of over four million women in England has revealed that women with endometriosis-associated infertility are significantly more likely to become pregnant compared to those with infertility from other causes.

1.841. Wearable X-ray-detecting fabric offers a flexible alternative to current imaging tech

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Since their discovery by Wilhelm Roentgen in 1895, X-rays have become a staple of modern medical care, from imaging teeth and broken bones to screening for the early signs of breast cancer.

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