Substance use implicated in most adult bath-related drownings

The number of colorectal cancer cases in people under 50 is rising worldwide, especially in high-income countries. Possible causes include Western diets, obesity, lack of exercise, and the use of antibiotics, especially in early life and adolescence.

People with poor mental health face many challenges. One that's perhaps lesser known is that they're more likely than the overall population to have poor oral health.

Candida auris is a dangerous fungal pathogen that has become a global health concern. It spreads easily in health care settings and can cause life-threatening infections, especially in patients with weakened immune systems. Alarmingly, it is often resistant to multiple antifungal drugs, making treatment difficult.

An article by Ph.D. student Ivonne Quiroz and colleagues published in the Journal of Agriculture, Food Systems, and Community Development assesses an online grocery ordering service implemented in rural Mississippi, where food insecurity and poor health outcomes are prevalent.

The hepatitis E virus (HEV) causes severe liver inflammation. A research team from Ruhr University Bochum, Germany, and TWINCORE, the Center for Experimental and Clinical Infection Research in Hannover, has now been able to prove for the first time that it can also infect kidney cells and replicate there. Antiviral drugs such as ribavirin are less effective there than in the liver. The results of the study have now been published in the journal Liver International.

Around 1 in 6 older adults take aspirin as their primary method of preventing cardiovascular disease—despite stricter guidelines that no longer always call for it, a study finds.

Three years ago, the U.S. Supreme Court struck down the constitutional right to abortion care established by Roe v. Wade in 1973, leaving abortion access decisions to the states. To date, 13 states have a complete abortion ban and seven ban abortion at or before 18 weeks' gestation.

Cancer cells have the capacity to multiply rapidly. The aggressive cancer cells undergo conversion from their tightly connected epithelial state into a mesenchymal state, which lacks contact restrictions and spreads easily to other parts of the body. Such epithelial-to-mesenchymal plasticity also makes the cancer cells resistant to elimination by anticancer therapies.

Young people with friends who vape are 15 times more likely to use e-cigarettes, and more adolescents are turning to illicit cannabis products, University of Queensland research has found.

Scientists from QIMR Berghofer's Cardiac Bioengineering Lab have developed lab-grown, three-dimensional heart tissues known as cardiac organoids that mimic the structure and function of real adult human heart muscle.

A joint study has evaluated the usability of a compact EEG device (BrainStatus) developed by Bittium Biosignals from Oulu during ambulance transports. The research was conducted by the Imaging center and Neurocenter of Kuopio University Hospital, the emergency medical services of the Wellbeing Services County of North Savo, and the University of Eastern Finland. The findings are published in the journal PLOS One.

A rare cell in the lining of lungs is fundamental to the organ-wide response necessary to repair damage from toxins like those in wildfire smoke or respiratory viruses, Stanford Medicine researchers and their colleagues have found. A similar process occurs in the pancreas, where the cells, called neuroendocrine cells, initiate a biological cascade that protects insulin-producing pancreatic islet cells from damage.

Advanced treatments, known as immunotherapies that activate T cells—our body's immune cells—to eliminate cancer cells, have shown limited efficacy as standalone therapies for glioblastoma, the most lethal form of brain tumor. This is due to their minimal response to glioblastoma and high resistance to treatment.

Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was trying to record electrical currents inside the neurons of squids.

Water fluoridation is effective in preventing tooth decay overall, but there are greater benefits for children from lower socioeconomic backgrounds, University of Queensland research has found.

Psilocybin, a psychedelic compound contained in some varieties of mushrooms, has recently been found to be promising for the treatment of some neuropsychiatric disorders, including depression, some anxiety disorders and post-traumatic stress disorder(PTSD). Some studies suggest that the consumption of this compound may be particularly advantageous for individuals who struggle to adapt their behavior in helpful ways when facing unexpected events or changes in their environment.

The University of Minnesota is stepping up efforts to identify biological threats that could trigger an epidemic, launching an institute to track disease-spreading infectious pathogens at the genetic level and monitor wastewater statewide.

Capital Medical University, in collaboration with the Chinese Academy of Sciences, reports that betaine, a molecule produced in the kidney and enhanced through sustained exercise, operates as a potent inhibitor of inflammatory and aging-related pathways.