Recurrence-free survival longer with nivolumab than ipilimumab in melanoma: Study
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- 2025-10-22 02:59 event
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Less than half of schoolchildren in England who are at risk of a serious and potentially life-threatening allergic reaction (anaphylaxis) to food were prescribed the antidote—an adrenaline [epinephrine] autoinjector, or AAI for short—finds an analysis of national prescribing data, published online in the Archives of Disease in Childhood.
Antidepressants can differ widely in how they physically affect the body, including around a 4 kg difference in weight change between certain drugs (approximately 2.5 kg weight loss from agomelatine and 2 kg weight gain from maprotiline), confirms a systematic review and meta-analysis published in The Lancet.
Clocking up at least 4,000 daily steps on just one or two days per week is linked to a lower risk of death and cardiovascular disease among older women, finds research published online in the British Journal of Sports Medicine.
An international research team led by Maggie Wong at the Max Planck Institute for Psycholinguistics (MPI) has discovered that SETBP1 missense variants outside the canonical degron region can disrupt DNA binding, transcriptional regulation, and neuronal differentiation—giving rise to a distinct, clinically heterogeneous neurodevelopmental disorder.
A study conducted by the Faculty of Sport and Health Sciences at the University of Jyväskylä, Finland, suggests that using an infrared sauna after exercise can speed up recovery and support performance in team-sport athletes. This method appears particularly promising during busy match schedules.
Doctors and scientists reported a case of Seoul virus infection in a woman. The Seoul virus belongs to the hantavirus family and can be transmitted by rats. In their publication of the case in the journal Emerging Infectious Diseases, the experts recommend better screening and improved hygiene practices in private rat breeding facilities. They also advocate for raising public awareness of zoonoses, which are diseases that can be transmitted from animals to humans.
A noninvasive MRI technique that measures volumetric changes in paraspinal muscles could transform how doctors assess nerve damage in the cervical spine, which helps guide more precise treatment decisions and potentially speed recovery for patients suffering from either sudden trauma or gradual degeneration.
A new study published in Behavior Genetics offers a fresh and nuanced perspective on the ongoing debate over social media's impact on well-being.
Delays in language and reading development are common, and learning disorders such as dyslexia can significantly affect a child's educational path and later opportunities. The earlier support is given, the easier it is for children to build strong language and reading skills.
For patients with resected stage IIIB-C or stage IV melanoma, recurrence-free survival is longer with nivolumab than ipilimumab, according to a study published online Oct. 18 in the New England Journal of Medicine to coincide with the annual meeting of the European Society for Medical Oncology, held from Oct. 17 to 21 in Berlin.
New longitudinal research reveals that severe stress caused by changes in family structure like divorce or separation experienced during the first year of life may triple the risk of developing psoriasis later in life.
In 2011, a rare type of Salmonella was reported for the first time in Europe connected to an outbreak in several European countries. At the time, outbreak investigations pointed to small tomatoes from Sicily (Italy) as the likely source for the salmonellosis cases caused by Salmonella Strathcona.
A new study from Wake Forest University School of Medicine, published online in Global Advances in Integrative Medicine and Health, reveals that use of a brief, noninvasive intervention offers meaningful relief for health care workers in the reduction of stress-related symptoms. This approach uses acoustic neuromodulation guided by each participant's unique brainwave activity, creating tailored sound sequences that help restore balance and reduce stress-related symptoms.
Prostate cancer relies on genetic "switches," called enhancers, that can turn on tumor-promoting genes. Researchers at the University of Michigan Health Rogel Cancer Center have discovered histone H2B N-terminal acetylation (H2BNTac), an essential chemical mark of these enhancers. They further implicate two proteins, p300 and CBP, that add these marks, and along with the androgen receptor, turn on enhancers and promote prostate cancer growth.
Nearly a decade ago, Kristen Beavers, who studies safe ways for older adults to lose weight, began asking whether weighted vests could help this population drop pounds without sacrificing vital bone mass and lean muscle. Now, in 2025, she routinely gets requests from national media, community groups and individuals interested in better ways to work out.
An international research team led by the Medical University of Vienna has demonstrated for the first time that thyroid hormone plays a key role in the development and progression of prostate cancer. By blocking a specific thyroid hormone receptor, cancer growth was inhibited in both animal models and tumor cell cultures.
A few years ago, I climbed over a gate and found myself gazing down at a valley. After I'd been walking for a few minutes, looking at the fields and the sky, there was a shift in my perception. Everything around me became intensely real. The fields and the bushes and trees and the clouds seemed more vivid, more intricate and beautiful.
Know someone who's been diagnosed with breast cancer? There's a good chance that person has received hormone therapy. Estrogen receptor-positive (ER+) breast cancers account for about 75% of cases. Hormone therapy is one of the most common and effective treatments. However, it's far from a cure.
A major study has found that babies born between 8 and 10 weeks early can be fed with milk through a tube in their stomach straight after birth rather than being given intravenous feeds through a drip.