Researchers link CAR-T cell aging to cancer relapse
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- 2025-07-14 23:23 event
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A multidisciplinary guideline panel convened by the American Association of Bronchology and Interventional Pulmonology (AABIP) and the Early Detection & Screening Committee of the International Association for the Study of Lung Cancer (IASLC) has determined that guided-bronchoscopy sampling provides tissue of comparable adequacy for comprehensive biomarker testing to percutaneous (CT-guided) biopsy, while delivering a superior safety profile—especially when contemporary navigational technologies are employed.
New research from The University of Texas at Austin suggests that exercising more frequently—ideally every day—could improve sleep quality, particularly the kind of deep, restorative sleep that supports better mood and mental health.
Observational studies of psychiatric diseases such as schizophrenia, bipolar disorder and major depression have long tied viral infections with behavioral symptoms in these disorders, but scientists have been unable to find direct evidence of suspected viruses in the brain. Experts say that's possibly because viruses may not get directly inside the brain, but may target the brain lining instead.
A new study has found clear evidence of inappropriate prescribing of antipsychotic treatments to children and young people (CYP) and low levels of aftercare monitoring by GPs and also raises concerns about the clarity of best practice guidelines across different care settings and the completeness of data available to researchers.
A new study led by Michigan State University found that as people get better at handling stress on a daily basis, they also become more extroverted, agreeable and open to new experiences over a nearly 20-year period. Likewise, the worse they manage daily stressors, the more introverted, unfriendly and closed off from new experiences they become.
Traditionally, individuals asked health questions of their primary health care provider. Confidence in that provider as a source of trustworthy health information has been consistently high in recent years and was at 90% in April, according to survey data from the Annenberg Public Policy Center (APPC) of the University of Pennsylvania.
They've barely opened their eyes, but newborn babies already seem to prefer nice behaviors.
A new study conducted by researchers from McGill University, the Lady Davis Institute for Medical Research (LDI) at the Jewish General Hospital, Princess Margaret Cancer Center and MIT has identified a novel approach to combat aggressive breast cancers by retraining neutrophils, the body's first responders, to directly kill tumor cells. This research offers new hope for patients with breast cancers that do not respond well to existing immunotherapies.
In a landmark discovery, researchers from QIMR Berghofer in collaboration with the Francis Crick Institute, have unlocked the secrets of how brain stem cells enter and exit a resting state called "quiescence"—a process with roots stretching back to the dawn of life. Their findings, published in Science Advances, may lead to new approaches in brain health and cancer therapy.
Mayo Clinic researchers have discovered a key reason some cancer patients relapse after receiving chimeric antigen receptor T-cell therapy, or CAR-T cell therapy. Over time, the engineered immune cells age and lose their ability to fight cancer.
Imagine walking into your doctor's office feeling sick—and rather than flipping through pages of your medical history or running tests that take days, your doctor instantly pulls together data from your health records, genetic profile and wearable devices to help decipher what's wrong.
A vaccine protects more than 100 million infants each year from severe tuberculosis (TB), including the fatal brain swelling it can cause in babies and toddlers. But the vaccine doesn't prevent adults from developing the more common form of TB that attacks the lungs. This allows TB to persist as the world's deadliest infectious disease, killing 1.25 million people a year.
Tumors can destroy the blood vessels of muscles even when the muscles are nowhere close to the tumor. That is the key finding of a new study that my colleagues and I recently published in the journal Nature Cancer.
Endocrine Society experts encouraged more widespread screening for a common hormonal cause of high blood pressure known as primary aldosteronism in a new Clinical Practice Guideline.
Menzies School of Health Research has led the largest-ever study of people living with a unique strain of chronic hepatitis B (C4 hepatitis B)—which predominately affects First Nations Australians in the Northern Territory (NT)—uncovering significant impacts on liver health.
Researchers at the Hebrew University have developed an exceptionally accurate method for predicting chronological age from DNA, based on two short genomic regions. Using deep learning networks analyzing DNA methylation patterns at a single-molecule resolution, they achieve age predictions with a median error as low as 1.36 years in individuals under 50. The method is unaffected by smoking, BMI, and sex, and has potential applications in forensics, aging research, and personalized medicine.
Alcohol has many negative effects on our health, some of which may surprise you. These include short-term impacts such as waking up with a pounding head or anxiety, to long-term effects including cancer.
More than 7 million people in the United States live with Alzheimer's disease and related dementia (ADRD). Some risk factors for ADRD, like genetics, can't be controlled, but others can be treated. One of the most prevalent is depression (known clinically as major depressive disorder, or MDD). Between 11.1% and 14.7% of ADRD cases—affecting roughly 1 million individuals in the US—are attributable to MDD.
The devastating losses from the historic flooding in Texas Hill Country on July 4, 2025, are still coming into grim focus, with 121 deaths confirmed and more than 100 still missing as of July 10.