Royalty-based investment model could bridge 'valley of death' between drug discovery and delivery

Ancient DNA has revealed a genetic link between the cultures of ancient Egypt and Mesopotamia, according to research published Wednesday in the journal Nature.

After following a protocol of sensory-motor activities with cognitive engagement for two months, eleven children aged 10 to 12 who were diagnosed with dyslexia showed improvement in reading speed. This initiative combined recreational activities that incorporated motor and social skills, demonstrating promise in improving children's reading performance.

A new national study led by researchers at the University of Delaware and George Mason University highlights significant disparities in health care access for adults with disabilities during the COVID-19 pandemic, particularly for preventive cardiovascular screenings.

UCLA researchers have developed an AI system that turns fragmented electronic health records (EHR) normally in tables into readable narratives, allowing artificial intelligence to make sense of complex patient histories and use these narratives to perform clinical decision support with high accuracy. The Multimodal Embedding Model for EHR (MEME) transforms tabular health data into "pseudonotes" that mirror clinical documentation, allowing AI models designed for text to analyze patient information more effectively.

Excessive physical exercise, especially without adequate rest, can damage the human body in various ways. In severe cases, it can progress to overtraining syndrome, which is characterized by decreased performance and appetite, chronic fatigue, muscle pain, increased injuries, and changes in the immune system and metabolism.

By creating artificial aging in mice, researchers at Lund University in Sweden have been able to track the formation of aneurysms in the walls of blood vessels.

A research team at the Universitat Oberta de Catalunya, working with the Hospital Sant Pau in Barcelona, has shown that theater can improve the emotional well‐being of people with Parkinson's disease. The study, "Efficacy of a theatre‐based intervention in patients with Parkinson's disease," which has been published in the journal Arts & Health, has provided the first evaluation of the combined effects of active and passive participation in theater activities on these patients' emotional and cognitive health and quality of life.

Mammograms can find cancer early before symptoms appear. Regular screening decreases the risk of dying from breast cancer. But a recent survey question by the Annenberg Public Policy Center shows that some Americans appear to be confused about when women with an average risk of breast cancer should begin a regimen of regular mammograms.

Bite the inside of your cheek, and the wound may vanish without a trace in a couple of days. A preclinical study co-led by Cedars-Sinai, Stanford Medicine and the University of California, San Francisco (UCSF), has discovered one secret of this disappearing act. The findings, if confirmed in humans, could one day lead to treatments that enable rapid, scarless recovery from skin wounds on other parts of the body.

A team of researchers from the San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET, Milan), led by Nadia Coltella and Luigi Naldini, has unveiled a powerful strategy to rejuvenate the effectiveness of chimeric antigen receptor (CAR) T cell therapy against glioblastoma, one of the most lethal and treatment-resistant brain tumors.

In August 2024, the World Health Organization declared a second "Public Health Emergency of International Concern" for mpox. The current outbreak in Africa is driven mainly by the clade I variant, with multiple countries reporting their first-ever mpox cases of this more severe strain.

Expressing love may lead to increased feelings of being loved, which can have downstream effects on people's senses of fulfillment and well-being. Researcher Zita Oravecz and colleagues from Pennsylvania State University, U.S., present these findings in a study published in PLOS One from a survey tracking feelings and acts of love over time.

A new study by researchers from the University of Birmingham, UCL, Great Ormond Street Hospital and Birmingham Children's Hospital has revealed important clues into what is driving disease in children with arthritis.

Prenatal exposure to ambient fine particulate matter and climatic factors, such as temperature and rainfall, are associated with adverse birth outcomes in India, according to a study published in PLOS Global Public Health by Mary Abed Al Ahad from the University of St Andrews, U.K.

Scopolamine, more chillingly known as "devil's breath," is a drug with a dual identity. In medicine, it's used to prevent motion sickness and nausea. But in the criminal underworld, particularly in parts of South America, it has gained a dark reputation as a substance that can erase memory, strip away free will and facilitate serious crimes. Now, its presence may be sparking fresh concerns in the UK.

UCLA researchers have successfully grown miniature lungs from stem cells—complete with their own functioning blood vessel networks.

The US Food and Drug Administration (FDA) has issued an urgent warning about tianeptine—a substance marketed as a dietary supplement but known on the street as "gas station heroin."

A creative play program has significantly improved new parents' and caregivers' mental health, according to research by the universities of Leeds and Huddersfield.