Seed oils aren't the problem—how we consume them is

Multidrug-resistant organisms (MDROs) are a major challenge in everyday medical practice, as they often cannot be treated with antibiotics. According to the Robert Koch Institute, there are 400,000 to 600,000 infections with hospital germs in Germany every year—around 10,000 to 20,000 people die from them. Alternative treatment options are therefore needed.

Emeli Chatterjee, Ph.D., of the Cardiovascular Research Center at Massachusetts General Hospital, is the lead author and Saumya Das, MD, Ph.D., of the Division of Cardiology at Massachusetts General Hospital, is the senior author of a paper published in Cell Genomics, titled "The extracellular vesicle transcriptome provides tissue-specific functional genomic annotation relevant to disease susceptibility in obesity."

Australians have long been some of the highest users of herbal and nutritional supplements that claim to boost mood or ease depression. These include omega-3s (found in fish oil), St John's wort, probiotics and vitamin D.

Immune checkpoints are regulatory proteins that prevent the immune system from attacking healthy tissues. Some cancer cells exploit these checkpoints to avoid immune detection. Immune checkpoint blockade (ICB)—a therapy that uses antibodies to block these deceptive signals—can unleash the immune system to destroy cancer.

Your feet do more than get you from place to place—they're key to your overall health.

Ultrasound (US) imaging is a widely employed diagnostic tool used for real-time imaging of various organs and tissues using ultrasonic sound waves. The waves are sent into the body, and images are created based on how the waves reflect off internal tissues and organs. It is used for guiding many medical procedures, including biopsies and injections, and is important for dynamic monitoring of blood vessels.

Penn Medicine researchers have identified genetic conditions in a large percent of adults admitted to the intensive care unit, dispelling the belief that genetic testing only benefits a pediatric population.

Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have identified a previously overlooked protein, Epac1, as a key driver of idiopathic pulmonary fibrosis (IPF), a chronic and progressive lung-scarring disease. Their findings, demonstrated across cell cultures, preclinical models, and samples of human lung tissue, show that blocking Epac1 can slow the progression of the disease.

New research explains how low levels of the electrolyte sodium in the blood can disrupt the timing of the heartbeat in patients taking widely used rhythm-control medications such as flecainide, which is commonly prescribed for atrial fibrillation and other fast or irregular heart rhythms.

A population-based cohort study emulating a target trial estimated the effect of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) compared with sodium-glucose cotransporter-2 (SGLT-2) inhibitors on the risk for gastroesophageal reflux disease (GERD) and its complications in patients with type 2 diabetes.

In a new mouse study, researchers have used optical coherence tomography (OCT) to uncover new insights into how the fallopian tube transports preimplantation embryos toward the uterus for pregnancy. These findings help lay the foundation for understanding certain causes of infertility and pregnancy complications in people.

An AI model trained to detect abnormalities on breast MR images accurately depicted tumor locations and outperformed benchmark models when tested in three different groups, according to a study published in Radiology.

Researchers from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and ETH Zurich have created the first integrated map detailing the metabolic and molecular changes in human blood stem cells as they age, specialize, or turn cancerous. Their innovative research, made possible by highly sensitive low-input techniques, identifies the nutrient choline as a key player in preserving youthful stem cell traits. This work offers profound insights into stem cell health and disease, suggesting promising directions for nutritional and therapeutic interventions to maintain a healthy blood system.

An unusual DNA structure may hold the key to treating one of the deadliest cancers affecting women, which claims more than 200,000 lives globally each year.

A Flinders University study shows that bowel cancer survivors face an elevated risk of developing multiple primary cancers (MPCs)—for prostate, lung, breast and blood cancer.

Penicillins are first-choice antibiotics for many common infections, but more than one in 15 UK adults have a penicillin allergy label on their medical records. In the event of an infection, they will be prescribed alternative antibiotics which can be less effective or have more side effects. This can result in several prescriptions being issued to control the infection, which affects well-being and contributes to antimicrobial resistance.

Genetic changes can signal evidence of disease, but pinpointing which genes and what's changed can be difficult.

Why do violent conflicts between groups persist—even when all sides suffer as a result? Researchers from psychology and medicine at Heinrich Heine University Düsseldorf (HHU) have now examined the dual effect of physiological stress messengers on social behavior in intergroup conflicts.