Smartphone tests could accelerate drug development for Huntington's disease

A new study on women's sexual experiences has challenged the commonly-held belief that reaching orgasm during sex is the single, essential indicator of a successful sexual encounter or a satisfying sexual relationship.

Atrial fibrillation is a common type of heart rhythm disorder where the heart doesn't beat efficiently. This makes the heart unable to pump enough blood out to the body with each heartbeat. It's estimated 12.1 million people in the U.S. will be diagnosed with AFib by 2030.

Every day, firefighters are exposed to cancer-causing chemicals from the scorched aftermath of forest fires, the melting pot of kitchen cleaning supplies in burning homes, and abandoned polyurethane appliances and bags in homeless encampment blazes.

Dementia before age 80 is potentially preventable through early intervention on common vascular risk factors, according to research led by the Johns Hopkins Bloomberg School of Public Health. Findings suggest that up to 44% of dementia cases could be attributed to vascular risk factors, specifically hypertension, diabetes, or smoking.

The World Health Organisation said Monday that the mpox virus epidemic remains an international health emergency with more than 37,000 confirmed cases reported since it erupted.

An international team of researchers led by King's College London has identified genetic factors that may make some individuals more or less sensitive to the environments they experience.

US Health Secretary Robert F. Kennedy Jr. on Monday announced he was dismissing all current members of a key federal vaccine advisory panel, accusing them of conflicts of interest—his latest salvo against the nation's immunization policies.

Children in rural Australia are missing out on critical early health supports, with limited access to allied health services putting them at greater risk of lifelong developmental challenges.

A Cleveland Clinic study shows that semaglutide and tirzepatide—injectable GLP-1 drugs for obesity—produce smaller weight loss in a real-world setting because patients discontinue treatment or use lower maintenance dosages. Treatment discontinuation also negatively impacted blood sugar control in patients with prediabetes. The study was published in the Obesity Journal.

Patients with womb cancer are not being tested for a genetic condition that increases their chance of developing further cancers, a study has found. The work is published in the journal BMJ Oncology.

Approximately 10% of the human population is left-handed. Among them, one in five exhibits a peculiar brain phenomenon known as atypical language lateralization. While most people attribute their language capability to their left hemisphere, this atypical group of left-handers utilizes their right hemisphere to speak. One of the oldest questions in neuroscience is how this phenomenon impacts brain organization and human behavior.

Cocaine, a drug of abuse, activates just a portion—10% to 20%—of the neurons in the brain's nucleus accumbens, a critical region linked to motivation and addiction. Though small in numbers, this activated neuronal population strongly controls drug-related behavior through downstream changes in gene expression, nerve synapses, neural circuitry and neural function that lead to behavioral change, including addiction.

In a study estimating the incidence rates of appendiceal adenocarcinoma (AA), or appendix cancer, across birth cohorts in the United States, researchers observed a sharp increase in AA incidence rates for those born after 1945, particularly for Generation X and Millennials. These patterns suggest a timely need for etiologic research and increased AA awareness among physicians and the public.

In Brazil, there is still no advanced therapy product for the treatment of chronic wounds and burns that has been registered with health regulatory bodies. A startup based at the Supera Innovation and Technology Park in Ribeirão Preto, in the interior of the state of São Paulo, intends to break down this barrier and become a pioneer in this segment.

A salmonella outbreak tied to a major egg recall has sickened nearly 80 people and sent at least 21 to the hospital, health officials have said.

Exercising during chemotherapy and before surgery may help the body send more immune cells into cancerous tumors, according to a first-of-its-kind pilot study from the University of Surrey and Royal Surrey NHS Foundation Trust.

Using a modern imaging technology known as cryo-electron microscopy, researchers at UT Southwestern Medical Center have determined the structure of a protein called midnolin that's crucial to the survival of malignant cells in some leukemias, lymphomas, and multiple myelomas. Their findings, published in PNAS, provide insight into how this protein functions in cells and could inform the design of new pharmaceuticals that avoid the serious side effects of current therapies.

Researchers from the Biostatistics Unit at the Germans Trias i Pujol Research Institute (IGTP) have led a study, published in BMJ Open, which analyzes how in-hospital mortality evolved during four waves of the COVID-19 pandemic in Catalonia, taking into account the patients' ceiling of care.