Study: Appendix cancer incidence has quadrupled in older Millennials

The World Health Organisation said Monday that the mpox virus epidemic remains an international health emergency with more than 37,000 confirmed cases reported since it erupted.

An international team of researchers led by King's College London has identified genetic factors that may make some individuals more or less sensitive to the environments they experience.

US Health Secretary Robert F. Kennedy Jr. on Monday announced he was dismissing all current members of a key federal vaccine advisory panel, accusing them of conflicts of interest—his latest salvo against the nation's immunization policies.

Children in rural Australia are missing out on critical early health supports, with limited access to allied health services putting them at greater risk of lifelong developmental challenges.

A Cleveland Clinic study shows that semaglutide and tirzepatide—injectable GLP-1 drugs for obesity—produce smaller weight loss in a real-world setting because patients discontinue treatment or use lower maintenance dosages. Treatment discontinuation also negatively impacted blood sugar control in patients with prediabetes. The study was published in the Obesity Journal.

A series of digital tests carried out via a smartphone app could enhance the detection of disease progression in Huntington's disease and improve the efficiency of clinical trials, finds research led by scientists at University College London (UCL) and Roche.

Patients with womb cancer are not being tested for a genetic condition that increases their chance of developing further cancers, a study has found. The work is published in the journal BMJ Oncology.

Approximately 10% of the human population is left-handed. Among them, one in five exhibits a peculiar brain phenomenon known as atypical language lateralization. While most people attribute their language capability to their left hemisphere, this atypical group of left-handers utilizes their right hemisphere to speak. One of the oldest questions in neuroscience is how this phenomenon impacts brain organization and human behavior.

Cocaine, a drug of abuse, activates just a portion—10% to 20%—of the neurons in the brain's nucleus accumbens, a critical region linked to motivation and addiction. Though small in numbers, this activated neuronal population strongly controls drug-related behavior through downstream changes in gene expression, nerve synapses, neural circuitry and neural function that lead to behavioral change, including addiction.

In Brazil, there is still no advanced therapy product for the treatment of chronic wounds and burns that has been registered with health regulatory bodies. A startup based at the Supera Innovation and Technology Park in Ribeirão Preto, in the interior of the state of São Paulo, intends to break down this barrier and become a pioneer in this segment.

A salmonella outbreak tied to a major egg recall has sickened nearly 80 people and sent at least 21 to the hospital, health officials have said.

Exercising during chemotherapy and before surgery may help the body send more immune cells into cancerous tumors, according to a first-of-its-kind pilot study from the University of Surrey and Royal Surrey NHS Foundation Trust.

Using a modern imaging technology known as cryo-electron microscopy, researchers at UT Southwestern Medical Center have determined the structure of a protein called midnolin that's crucial to the survival of malignant cells in some leukemias, lymphomas, and multiple myelomas. Their findings, published in PNAS, provide insight into how this protein functions in cells and could inform the design of new pharmaceuticals that avoid the serious side effects of current therapies.

Researchers from the Biostatistics Unit at the Germans Trias i Pujol Research Institute (IGTP) have led a study, published in BMJ Open, which analyzes how in-hospital mortality evolved during four waves of the COVID-19 pandemic in Catalonia, taking into account the patients' ceiling of care.

Age-related macular degeneration (AMD) is a major cause of blindness, especially in older adults. A key feature of early AMD is the formation of drusen, clumps of debris made of lipids and proteins that collect between two layers at the back of the eye—the retinal pigment epithelium (RPE) and Bruch's membrane (BrM).

Hepatitis C virus (HCV) infection is highly associated with the development of metabolic dysfunction-associated steatotic liver disease (MASLD), with a diagnosis requiring the presence of steatotic liver disease (SLD) along with at least one of five cardiometabolic risk factors (CMRFs), including obesity, arterial hypertension (HTN), type 2 diabetes (T2D)/prediabetes, and dyslipidemia.

Just as folds are important in the ancient art of origami, they are also vital for the function of many proteins. Mutations in a protein associated with conditions such as seizures and autism spectrum disorder prevent it from folding correctly and hinder its movement to the cell surface, where it would normally do its job.

Northwestern University biophysicists have developed a new computational tool for identifying the gene combinations underlying complex illnesses like diabetes, cancer and asthma.