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Stress alters metabolic hormone with health consequences, study shows

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  • 2025-10-15 00:01 event
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Stress alters metabolic hormone with health consequences, study shows
A long-studied metabolic hormone, FGF21, also acts as a stress hormone—a discovery that helps explain how psychological stress causes metabolic dysregulation and drives physical disease, according to a new study from researchers at Columbia University Mailman School of Public Health, Columbia University Irving Medical Center, and the Butler Columbia Aging Center. The findings are published in Nature Metabolism.

20. FDA approves Jascayd for idiopathic pulmonary fibrosis

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The U.S. Food and Drug Administration has approved Jascayd (nerandomilast) tablets to treat idiopathic pulmonary fibrosis (IPF).

21. Newly identified function for protein could hold key to chemo resistance

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A University of Alberta research team has uncovered a new role for a genetic mutation previously known to be linked to developmental disorders—and it could hold the key to more effective treatments and improved outcomes for cancer patients.

22. Optical imaging technique unlocks hidden glycemic history for diabetes and cancer research

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A National Taiwan University (NTU) interdisciplinary research team, led by Prof. Chi-Kuang Sun and Prof. Tzung-Dau Wang, has unveiled a optical imaging technique that enables the reconstruction of an individual's historical blood glucose patterns—information that has long been beyond the reach of current medical technology.

23. Wind-blown dust from receding Salton Sea linked to reduced lung function in area children

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Children living near the Salton Sea, in Southern California's desert region of Imperial County, are experiencing poorer lung function than children exposed to less wind-blown dust, according to a new study led by researchers at the University of California, Irvine's Joe C. Wen School of Population & Public Health.

24. Researchers show a brain exercise yields benefits

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A McGill University-led clinical trial is the first in humans to show online brain training exercises can improve brain networks affecting learning and memory.

25. New imaging solution could help improve survival for patients with recurring prostate cancer

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A multicenter study led by London Health Sciences Centre Research Institute (LHSCRI), Lawson Research Institute of St. Joseph's Health Care London (Lawson), and University Health Network (UHN) has found a novel imaging solution, called prostate-specific membrane antigen (PSMA) positron emission tomography (PET) scanning, can more effectively detect the recurrence of prostate cancer compared to standard imaging methods, and is associated with improved survival outcomes. The study, carried out over seven years, is published in The Journal of Nuclear Medicine.

26. Approach–avoidance behavior can reshape how the brain interprets facial emotions

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A research team from the Cognitive Neurotechnology Unit and the Visual Perception and Cognition Laboratory at Toyohashi University of Technology has found that approach–avoidance behavior in a virtual reality (VR) environment modulates how individuals recognize facial expressions. Notably, the study demonstrated that participants were more likely to perceive a facial expression as "angry" when they actively moved away from the face stimulus than when the face moved away from them. These findings contribute to a better understanding of the reciprocal relationship between perception and action in social contexts.

27. Research paves the way for potential anti-ulcer vaccine

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Since ancient times, it was thought that painful stomach ulcers were caused by eating spicy foods or having an unhealthy diet. But since then, researchers have found that Helicobacter pylori—a common bacterium found in over 60% of the world's population—was the real culprit behind most stomach ulcers and a high risk for stomach cancer.

28. Glycation-lowering compounds curb hunger, lower insulin resistance and extend lifespan in mice

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The same chemical reaction that makes a piece of freshly toasted bread delicious also happens in our bodies, with far less appetizing consequences. We're talking about the Maillard reaction, where sugars react with protein to form brown, sticky compounds in a process called glycation. Glycation is increasingly suspected to be a hidden driver of obesity, diabetes and accelerated aging. Researchers in the Kapahi lab have found a way to tame it in mice by feeding them a combination of glycation-lowering compounds.

29. Stress alters metabolic hormone with health consequences, study shows

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A long-studied metabolic hormone, FGF21, also acts as a stress hormone—a discovery that helps explain how psychological stress causes metabolic dysregulation and drives physical disease, according to a new study from researchers at Columbia University Mailman School of Public Health, Columbia University Irving Medical Center, and the Butler Columbia Aging Center. The findings are published in Nature Metabolism.

30. Eco-friendly silicon patch delivers clearer ultrasound images without harmful lead components

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Wearable ultrasound devices are actively used in various medical settings, including hospital diagnostics, rehabilitation monitoring, and telemedicine. However, most commercial devices currently rely on lead (Pb)-based piezoelectric ceramics, which are harmful to the human body and the environment, making it difficult to ensure both performance and safety.

31. Early menopause associated with increased risk of dementia

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A new international study led by University of Galway has found that entering menopause at an earlier age is associated with an increased risk of dementia.

32. Teens who start drinking as early as 12 have much higher risk of alcohol-related harms

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The earlier teenagers begin drinking before the minimum legal age for purchasing alcohol, the higher the risk of heavy drinking and alcohol-related harms in early adulthood.

33. Peppermints improve alertness when sick with a cold, study suggests

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Eating peppermints can increase alertness in people who are ill with the common cold, according to new research by Cardiff University scientists.

34. Common hospice medications linked to higher risk of death in people with dementia

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Hospice care aims to bring comfort, peace, and dignity to patients at the end of life. Yet for the growing number of Americans with dementia who enter hospice, their course is often long and unpredictable—making it especially important to ensure treatments align with each person's goals and stage of illness.

35. Does catching up on sleep actually work?

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Imagine it's Saturday morning, the perfect time to slow down, relax and... pay off debt? That's how many Americans start their weekend. No, we're not talking about the credit card bill. Many Americans are in debt—sleep debt.

36. mRNA directs body to produce nanobodies that unlock immune attack on colorectal cancer tumors

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A tiny molecule called a nanobody may succeed where today's cancer drugs often fail, according to University of Hawaiʻi at Mānoa researcher Stefan Moisyadi, who has been refining the concept for nearly a decade.

37. New gene therapy shows promise in preventing kidney disease in type 1 diabetes

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A new gene therapy approach aimed at protecting people with type 1 diabetes from developing diabetic kidney disease—a serious and common complication of the condition, has shown promising results in a University of Bristol study.

38. AI predicts future X-rays to help osteoarthritis patients and their doctors see what's coming

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An AI system that can predict what a patient's knee X-ray will look like a year in the future could transform how millions of people with osteoarthritis understand and manage their condition, according to research by the University of Surrey.

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