Study: Quick, pain-free breast imaging system shows promise in early clinical tests

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a progressive neurological disease with an average age of onset at 43 years and an average life expectancy of only three to five years after symptoms begin. ALSP is caused by microglial mutations in the immune cells of the central nervous system (CNS). Currently, ALSP has no cure and treatments are limited.

In a follow-up analysis to the pivotal TOPAZ-1 study, which established the combination therapy of durvalumab (an immunotherapy drug) plus gemcitabine and cisplatin (GemCis, chemotherapy drugs) as the first-line treatment for people with advanced biliary tract cancer (aBTC), researchers have shown that after three years more than twice as many study participants treated with durvalumab plus GemCis had survived compared to those treated with a placebo plus GemCis.

Children with multiple long-term health issues undergo severe emotional stress at the same time as they are trying to cope with the physical challenges of their condition, a study published in the Journal of Affective Disorders has found.

Cambodia's Ministry of Health recently confirmed the country's twelfth human case of H5N1 avian influenza so far this year. The patient, a five-year-old boy from Kampot province, is currently in intensive care with severe respiratory symptoms.

A team has made a major breakthrough in the field of three-dimensional (3D) imaging of large-scale biological tissues. They developed the world's fastest high-definition 3D imaging technology for the entire body of small animals at subcellular resolution, enabling efficient mapping of the fine architecture of the peripheral nervous system (PNS). The findings were published in Cell.

Results of a Dana-Farber Cancer Institute-initiated phase 1 clinical trial for patients with melanoma show that an updated formula and delivery of the NeoVax personalized cancer vaccine called NeoVaxMI is safe, feasible, and improves the vaccine-specific immune response compared to previous trials of the platform.

A new wearable wristband could significantly improve diabetes management by continuously tracking not only glucose but also other chemical and cardiovascular signals that influence disease progression and overall health. The technology was published in Nature Biomedical Engineering.

Dr. Ho Sang Jung and his research team from the Advanced Bio and Healthcare Materials Research Division at the Korea Institute of Materials Science (KIMS) have developed an optical biosensor capable of detecting trace amounts of cancer cell DNA in the bloodstream with high sensitivity, enabling early cancer diagnosis.

Researchers at Karolinska Institutet have discovered a previously unknown molecule that may explain why people with type 2 diabetes often suffer from muscle weakness and muscle loss—a condition that has a major impact on quality of life and overall health.

Although the avian flu (H5N1) virus may not be making the news as frequently, it is still working hard behind the scenes, attempting to evolve into more and more effective versions. Since the highly pathogenic avian flu was detected in Canada in 2021, it has led to the infection of over 180 million domestic birds in Canada and the United States. New evidence published in Science Advances, indicates that the H5N1 virus has been intermixing with low-pathogenicity avian influenza viruses (LPAIVs) to expand its host options and geographical range.

The Chan Zuckerberg Initiative (CZI) reports its latest AI model aimed at helping researchers better understand how cells behave by focusing on the key networks that control cell behavior, making complex biological problems, like cancer, easier to solve.

The term "oral health" refers to the health of the mouth, teeth, gums, and other related structures, and it is closely linked with our well-being and quality of life.

If memories are the black box of our past, they can also shed light on the present by giving meaning to new situations. But how does memory retrieve either surface matches (based on same places, same people) or deeper, more conceptual ones (based on similar intentions or actions)?

Associations between hormone therapy and young-onset breast cancer (diagnosed at younger than 55 years) vary, according to a study published online in the July issue of The Lancet Oncology.

Doctors are at higher risk of depression, anxiety and suicide than almost any other profession. Now, a global review led by UNSW Sydney and Black Dog Institute reveals which intervention approaches can help—and where urgent research is still needed.

Hollywood has shaped how many people imagine a heart attack—someone clutching their chest and collapsing dramatically. But those portrayals are misleading and shouldn't be expected, says Ann Eckhardt, a nursing professor and researcher at The University of Texas at Arlington.

The World Health Organization defines IGD as a pattern of persistent or recurrent gaming behavior that takes precedence over other life interests and activities, resulting in significant impairment or distress.

As the summer's sunny days take hold, many people turn to outdoor exercise.