Study proposes new, more personalized methadone restart approach for opioid use disorder
- medicalxpress.com language
- 2025-08-28 22:00 event
- 3 weeks ago schedule

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Fewer than half of people diagnosed with a subtype of myeloid/lymphoid neoplasms are alive one year later. A multicenter Phase II trial, called FIGHT-203, led by Stanford Medicine, has led to FDA approval of a new drug treatment.
Testing the molecular profile of tumors identifies which patients with advanced prostate cancer are more likely to benefit from chemotherapy and live longer, sparing patients less likely to benefit from unpleasant side effects, according to a new study led by UCL researchers.
New proteomics research is enabling scientists to decipher how neurotransmitter receptors behave and change as an organism develops. The new work could help scientists better understand the formation and function of synapses—the junctions where communication signals are passed between neurons.
People with rheumatoid arthritis (RA) often have trouble getting out of bed in the morning, let alone getting to the rheumatologist for a checkup or participating in a research study. This makes a deeper understanding of the mysterious autoimmune disease all the more difficult. That's a significant problem, because RA affects more than 1.5 million people in the U.S. and 18 million people worldwide—and as of now, there's no cure.
A new global systematic literature review and meta-analysis has shown that herpes zoster vaccination, used to prevent shingles, is associated with a statistically significant lower risk of heart attack and stroke.
My travels with autism started long before my diagnosis, at the age of three years and three months.
Queensland woman Amanda Maree Power has recently been jailed after faking cancer and fraudulently raising about A$24,000 from friends, family and strangers over several years—including to pay for holidays and fake medical bills.
A new study by researchers at the University of Exeter has found that routine blood tests used in primary care to assess anemia and mean corpuscular volume (MCV) are more effective at predicting cancer risk in white patients than in Asian or Black patients.
Guidance around COVID-19 vaccines has once again shifted after the Food and Drug Administration on Aug. 27, 2025, approved updated shots for the fall season, but for a more limited group than in prior seasons.
A new study by University of Colorado Anschutz and Denver Health researchers, published in JAMA Network Open, introduces a more individualized approach to restarting methadone treatment for people with opioid use disorder. The findings suggest that tailoring methadone doses to each patient's unique circumstances can improve care without compromising safety.
Researchers have reported results from the first-ever clinical trial of a new class of targeted therapy in pet cats with head and neck squamous cell carcinoma (HNSCC)—a cancer which is notoriously deadly and difficult to treat. Published in Cancer Cell, the study found that 35% of the cats who received treatment had their disease controlled with minimal side effects—and the drug will likely be effective for humans with HNSCC as well.
How can we live longer? The eternal question, and one that scientists have long been trying to answer.
Conventional wearable sweat sensors utilize hydrophobic ion-selective membranes (ISMs) and require tight contact and adhesives to achieve signal stability. However, this can lead to user discomfort and skin-related diseases, necessitating the development of non-contact alternatives. In a new study, inspired by the self-cleaning behavior of rose petals, researchers developed novel ISM-based sweat sensors that feature enhanced signal stability and performance, avoid skin contact, and are reusable, making them practical for daily use.
Kruti Naik, a Ph.D. candidate in ocular drug delivery at the Wits Advanced Drug Delivery Platform (WADDP) at Wits University, could change the way eye infections and conditions are treated. Eye drops are the go-to treatment, but Naik is determined to find efficient and cheaper ways to treat vision problems.
Researchers at McGill University and the Douglas Institute have identified two specific types of brain cells that are altered in people with depression.
A new diagnostic method would confirm sepsis infections earlier, cutting critical hours in the "race against time" to save patients' lives.
A University of Otago–Ōtākou Whakaihu Waka researcher is calling for urgent and targeted regulatory action towards vaping, as her recent research shows the discreet design of vaping devices has fostered vaping normalization and uptake among young Māori.
A new report provides an overview of the legal, ethical, and policy questions raised by in vitro gametogenesis (IVG)—the creation of lab-grown eggs and sperm.
University of North Carolina researchers affiliated with the School of Nursing and School of Medicine contributed to new blood pressure guidelines released by the American Heart Association and American College of Cardiology.