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Molecular test helps tailor chemotherapy for advanced prostate cancer patients

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  • 2025-08-28 22:42 event
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Molecular test helps tailor chemotherapy for advanced prostate cancer patients
Testing the molecular profile of tumors identifies which patients with advanced prostate cancer are more likely to benefit from chemotherapy and live longer, sparing patients less likely to benefit from unpleasant side effects, according to a new study led by UCL researchers.

1.408. AI tool enhances flu vaccine strain selection

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Every year, global health experts are faced with a high-stakes decision: Which influenza strains should go into the next seasonal vaccine? The choice must be made months in advance, long before flu season even begins, and it can often feel like a race against the clock. If the selected strains match those that circulate, the vaccine will likely be highly effective. But if the prediction is off, protection can drop significantly, leading to (potentially preventable) illness and strain on health care systems.

1.409. Understanding how human cytomegalovirus manipulates our DNA

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Northwestern Medicine scientists have discovered how a common virus linked to birth defects and chronic illness manipulates its host's DNA, according to a new study published in Nature Communications.

1.410. The brain's activity at rest may provide clues to Alzheimer's disease progression and diagnosis

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Some regions of the brain in people with Alzheimer's reorganize more often while at rest than in people without the disease––and in healthy people this frequent reshuffling sometimes predicts who will develop the condition later, according to a new study from the University of Michigan and Columbia University.

1.411. Novel blood test for ALS can detect early signs years before symptoms appear

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By 2040, experts estimate that nearly 400,000 people worldwide will be living with amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig's disease. This degenerative nervous system disease damages nerve cells responsible for controlling voluntary muscle movement, leading to progressive muscle weakness, loss of muscle mass and, eventually, difficulty breathing. Current ALS diagnosis relies on neurological evaluations and the presence of symptoms; at present, there is no definitive diagnostic test.

1.412. Clinical trial tests speech therapy for rare neurological disorder

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Researchers have led the largest clinical study to date investigating speech therapy for people with a rare, rapidly progressive and fatal neurological condition.

1.413. Potential new target points to non-addictive treatments for relieving pain after surgery

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A University of Alberta-led team has identified a new way to treat post-surgical pain in animals and human cells, in a bid to find non-addictive treatments for acute and even chronic pain.

1.414. Analysis aims to ease GI symptoms for cancer patients

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Many modern cancer treatments are highly effective at reducing or eliminating tumors, but they can also cause severe gastrointestinal symptoms that impact patients' quality of life or lead to discontinuation of treatment. A new analysis from University of Illinois Urbana-Champaign researchers reveals the nutrition therapies that are most effective at minimizing GI distress. The research is published in the journal Advances in Nutrition.

1.415. Guideline on respiratory infections in leukemia revised

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People with leukemia have a weakened immune system due to the disease itself and treatment, which leads to an increased susceptibility to infections. In a revised guideline, experts summarize the findings of the past ten years on all viruses that cause respiratory infections: How dangerous are they in detail? How are they diagnosed? Are hygiene measures necessary? What treatment and vaccination strategies are available?

1.416. Clinical trial leads to FDA approval of drug for rare, deadly blood cancer

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Fewer than half of people diagnosed with a subtype of myeloid/lymphoid neoplasms are alive one year later. A multicenter Phase II trial, called FIGHT-203, led by Stanford Medicine, has led to FDA approval of a new drug treatment.

1.417. Molecular test helps tailor chemotherapy for advanced prostate cancer patients

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Testing the molecular profile of tumors identifies which patients with advanced prostate cancer are more likely to benefit from chemotherapy and live longer, sparing patients less likely to benefit from unpleasant side effects, according to a new study led by UCL researchers.

1.418. Researchers detail how neurotransmitter receptors in the fly brain change during development

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New proteomics research is enabling scientists to decipher how neurotransmitter receptors behave and change as an organism develops. The new work could help scientists better understand the formation and function of synapses—the junctions where communication signals are passed between neurons.

1.419. Q&A: These genetic insights into rheumatoid arthritis could help design better treatments

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People with rheumatoid arthritis (RA) often have trouble getting out of bed in the morning, let alone getting to the rheumatologist for a checkup or participating in a research study. This makes a deeper understanding of the mysterious autoimmune disease all the more difficult. That's a significant problem, because RA affects more than 1.5 million people in the U.S. and 18 million people worldwide—and as of now, there's no cure.

1.420. Review and meta-analysis show an association between shingles vaccination and lower risk of heart attack, stroke

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A new global systematic literature review and meta-analysis has shown that herpes zoster vaccination, used to prevent shingles, is associated with a statistically significant lower risk of heart attack and stroke.

1.421. I'm autistic and don't speak: Here's what I want you to know

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My travels with autism started long before my diagnosis, at the age of three years and three months.

1.422. Why scammers fake illness for cash, according to a psychologist

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Queensland woman Amanda Maree Power has recently been jailed after faking cancer and fraudulently raising about A$24,000 from friends, family and strangers over several years—including to pay for holidays and fake medical bills.

1.423. Primary care study shows routine blood tests for cancer risk differ by ethnicity

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A new study by researchers at the University of Exeter has found that routine blood tests used in primary care to assess anemia and mean corpuscular volume (MCV) are more effective at predicting cancer risk in white patients than in Asian or Black patients.

1.424. FDA approves updated COVID-19 vaccines with new restrictions, potentially limiting access for healthy children

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Guidance around COVID-19 vaccines has once again shifted after the Food and Drug Administration on Aug. 27, 2025, approved updated shots for the fall season, but for a more limited group than in prior seasons.

1.425. Study proposes new, more personalized methadone restart approach for opioid use disorder

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A new study by University of Colorado Anschutz and Denver Health researchers, published in JAMA Network Open, introduces a more individualized approach to restarting methadone treatment for people with opioid use disorder. The findings suggest that tailoring methadone doses to each patient's unique circumstances can improve care without compromising safety.

1.426. Novel therapy for pet cats with head and neck cancers could help humans

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Researchers have reported results from the first-ever clinical trial of a new class of targeted therapy in pet cats with head and neck squamous cell carcinoma (HNSCC)—a cancer which is notoriously deadly and difficult to treat. Published in Cancer Cell, the study found that 35% of the cats who received treatment had their disease controlled with minimal side effects—and the drug will likely be effective for humans with HNSCC as well.

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