Sugar layer on beta cells prevents immune system from causing type 1 diabetes

Using a custom-built tool to analyze the electrical activity from neurons, researchers at Brown University have identified a brain-based biomarker that could be used to predict whether mild cognitive impairment will develop into Alzheimer's disease.

Biological sex affects hormonal and involuntary nervous system responses to binge drinking, potentially influencing vulnerability to alcohol use disorder (AUD). That's according to a new laboratory study examining the role of biological sex in the endocrine stress response to high-dose alcohol.

Cardiovascular tests performed during primary care visits may give evidence of increasing alcohol use, which could help clinicians identify and treat risky drinking behaviors early.

Understanding exactly how psychedelics promote new connections in the brain is critical to developing targeted, non-hallucinogenic therapeutics that can treat neurodegenerative and neuropsychiatric diseases. To achieve this, researchers are mapping the biochemical pathways involved in both neuroplasticity and hallucinations.

More than a decade ago, researchers found that an acute complication of type 1 diabetes, diabetic ketoacidosis (DKA), can be resolved with the hormone leptin, even in the absence of insulin.

When epidemiologist Daniela Gafita makes her rounds in the remote villages of northeastern Romania to educate communities about the risks of measles, she frequently encounters parents who hesitate to have their children vaccinated.

Ahead of the expected finalization of a UN global plastics treaty, a group of international experts calls for a greater focus on health impacts when considering plastic pollution. The Health Policy published in The Lancet reviews the current evidence on how plastics—including microplastics and plastic chemicals—impact health and announces the launch of a new project tracking these impacts: the Lancet Countdown on Health and Plastics.

A research team from Kumamoto University has made a new discovery that reveals how the human T-cell leukemia virus type 1 (HTLV-1) silently persists in the body. Their finding potentially lays the foundation for new therapeutic approaches. Their study, published in Nature Microbiology, identifies a previously unknown genetic "silencer" element that keeps the virus in a dormant, undetectable state.

In a study published in Advanced Materials, a research team developed an innovative bacterial cellulose (BC)-based hemostatic dressing that enables rapid and sustained bleeding control.

A new editorial published in Comprehensive Physiology underscores the critical importance of understanding heart-lung interactions in pulmonary vascular disease (PVD). Tim Lahm, MD, a pulmonologist and researcher at National Jewish Health, along with a team of esteemed colleagues from institutions across the country, urges the scientific community to confront the major knowledge gaps that hinder progress in improving patient outcomes.

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15–19 September) suggests that living in a rural environment in the first five years of life could increase the risk of developing type 1 diabetes compared with living in urban environments.

Cannabis use is gaining popularity in the United States, driven by growing legalization, public acceptance and diverse methods of consumption.

Play is how young children make sense of the world. Whether with dolls, blocks, trains, or playdough, children use play to explore, experiment, and learn. In early childhood, it is essential that children have at least an hour of open-ended play each day, as recommended by research. During this time, they should be encouraged to ask questions, test ideas and engage in creative thinking. Play is not just fun — it is foundational. Play supports cognitive growth, language and communication skills, social and emotional development, physical coordination, creativity, and overall school readiness.

In recent years, doctors and scientists are increasingly studying long-lasting illnesses that begin after someone recovers from an infection. Two of the most well-known examples are long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

Can simple words like "and" or "then" in online reviews help health care providers learn about their patients' experiences?

The federal government's Medicare program and older adults together spend $4.4 billion a year on care that has low clinical value for patients and can even raise their risk of harm, a new study finds.

A recent multicenter clinical trial has uncovered inflammatory pathways that contribute to asthma flare-ups in children that occur despite treatment, according to findings published in JAMA Pediatrics.

US pharmaceutical giant Pfizer and German firm BioNTech lost Friday a court appeal in the latest step of a multi-million pound battle against US rival Moderna over the COVID-19 vaccine.