Pfizer and BioNTech lose UK court appeal over COVID jab

Scientific breakthroughs in one disease don't always shed light on treating other diseases. But that's been the surprising journey of one Mayo Clinic research team. After identifying a sugar molecule that cancer cells use on their surfaces to hide from the immune system, the researchers have found the same molecule may eventually help in the treatment of type 1 diabetes, once known as juvenile diabetes.

A new editorial published in Comprehensive Physiology underscores the critical importance of understanding heart-lung interactions in pulmonary vascular disease (PVD). Tim Lahm, MD, a pulmonologist and researcher at National Jewish Health, along with a team of esteemed colleagues from institutions across the country, urges the scientific community to confront the major knowledge gaps that hinder progress in improving patient outcomes.

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15–19 September) suggests that living in a rural environment in the first five years of life could increase the risk of developing type 1 diabetes compared with living in urban environments.

Cannabis use is gaining popularity in the United States, driven by growing legalization, public acceptance and diverse methods of consumption.

Play is how young children make sense of the world. Whether with dolls, blocks, trains, or playdough, children use play to explore, experiment, and learn. In early childhood, it is essential that children have at least an hour of open-ended play each day, as recommended by research. During this time, they should be encouraged to ask questions, test ideas and engage in creative thinking. Play is not just fun — it is foundational. Play supports cognitive growth, language and communication skills, social and emotional development, physical coordination, creativity, and overall school readiness.

In recent years, doctors and scientists are increasingly studying long-lasting illnesses that begin after someone recovers from an infection. Two of the most well-known examples are long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

Can simple words like "and" or "then" in online reviews help health care providers learn about their patients' experiences?

The federal government's Medicare program and older adults together spend $4.4 billion a year on care that has low clinical value for patients and can even raise their risk of harm, a new study finds.

A recent multicenter clinical trial has uncovered inflammatory pathways that contribute to asthma flare-ups in children that occur despite treatment, according to findings published in JAMA Pediatrics.

A baby boy born last week to an Ohio couple developed from an embryo that had been frozen for more than 30 years in what is believed to be the longest storage time before a birth.

In a discovery that could guide the development of next-generation antidepressants and antipsychotic medications, researchers at the Icahn School of Medicine at Mount Sinai have developed new insights into how a critical brain receptor works at the molecular level and why that matters for mental health treatments.

Researchers have discovered a protein which is critical for steering melanoma cancer cells as they spread throughout the body. The malignant cells become dependent on this protein to migrate, pointing to new strategies for impeding metastasis.

Rheumatoid arthritis (RA) is a chronic autoimmune disease in which the immune system mistakenly attacks the lining of the joints (the synovium), causing pain, swelling, and progressive damage. Approximately 18 million people worldwide live with RA. Early diagnosis and treatment can relieve symptoms, slow disease progression, and help prevent disability.

For patients with eosinophilic granulomatosis with polyangiitis (EGPA), rituximab is not superior to the conventional remission induction strategy, according to a study published online July 29 in the Annals of Internal Medicine.

People with diabetes suffer from depression more frequently than average. Researchers from the German Diabetes Center (DDZ), the Research Institute of the Diabetes Academy Mergentheim (Forschungsinstitut an der Diabetes Akademie Mergentheim, FIDAM) and the German Center for Diabetes Research (DZD) were able to show in a large-scale analysis that biomarkers for chronic inflammation levels influence the therapeutic success of depressive symptoms—however, with considerable differences in type 1 and type 2 diabetes. The findings could help to customize the treatment of depression in people with diabetes in the future.

President Donald Trump has introduced a new effort to help Americans more easily share their health records with doctors, using new technology and artificial intelligence (AI) tools.

The earliest warning signs of multiple sclerosis (MS) may emerge more than a decade before the first classical neurological symptoms occur, according to new research from the University of British Columbia.

A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in T-cell development and function.