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During the early days of the COVID-19 pandemic, there was a decline in the physical fitness of U.S. youth, according to a study published online June 4 in JAMA Network Open.
A research team at Toho University has revealed that ferulic acid (FA), a polyphenol abundant in rice bran, suppresses intestinal smooth muscle contractions by inhibiting voltage-dependent calcium channels. This finding may open new avenues for dietary-based strategies to manage intestinal motility disorders such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).
About 525,000 more deaths occurred among US adults in 2023 than would be expected had pre-2010 mortality trends continued. More than 90% of these deaths occurred among individuals without a bachelor's degree and were largely caused by cardiovascular diseases, underscoring how educational attainment can influence individuals' health opportunities and outcomes.
Regular physical activity is increasingly promoted for people with rheumatic and musculoskeletal diseases (RMD) as well as the general population. EULAR—The European Alliance of Associations for Rheumatology—has published recommendations for physical activity in people with inflammatory arthritis and osteoarthritis. There are also points to consider on helping people participate in healthy and sustainable paid work.
Osteoarthritis is a leading cause of chronic pain, often affecting physical function, daily activities, and quality of life. EULAR—The European Alliance of Associations for Rheumatology—has developed recommendations and clinical practice guidelines for the management of osteoarthritis in the hand, hip, and knee.
EULAR—The European Alliance of Associations for Rheumatology—believes that nurses are an important part of the health care team, especially for providing evidence-based care and endorsing shared decision-making in consultation with the patient. This is also important considering the shortage of rheumatologists in Europe, which means delegation is necessary.
When receiving a diagnosis of a rheumatic musculoskeletal disease (RMD), people need a lot of information. Some need it all at once, while others may prefer to receive it in smaller portions or like to spread it out. This can mean that rheumatologists and other health care professionals do not always know how best to support patient education.
Rheumatic musculoskeletal diseases (RMD) have an important impact on quality of life, and represent an economic burden to society. EULAR—The European Alliance of Associations for Rheumatology—has emphasized the role of patient empowerment through education.
Rheumatic and musculoskeletal diseases (RMD) are the leading causes of disability worldwide, resulting in significant health care and social support costs. One of the reasons for this increasing burden seems to be the variability in the number and nature of allocated resources across Europe, as well as organizational aspects of health systems that result in disparities and health inequities across countries.
Diabetic foot ulcers (DFUs) are a major clinical challenge, with high rates of morbidity, disability, amputations and mortality. Despite extensive research, effective predictive biomarkers for DFUs healing remain elusive.
Chimeric antigen receptor (CAR)-T cells are a promising cancer therapy that are made from the patient's own T cells, which are reprogrammed to fight their cancer. One of the limitations of CAR-T cell therapy is the ability of these cells to survive long enough to target the entire tumor.
When a house is hit by a hurricane, you must first remove the damaged parts before reconstruction can begin. The same applies to our muscles after injuries—and now researchers from Aarhus University and Steno Diabetes Center Aarhus have discovered who functions as the coordinator of this repair process.
A novel immuno-PET/CT imaging technique has identified and validated a potent biomarker for nasopharyngeal cancer (NPC). The biomarker, CD70, is highly and constantly expressed in NPCs, and CD70-targeted immuno-PET/CT has proven effective in accurately detecting primary and metastatic NPC lesions.
The adoption of the WHO Pandemic Agreement by the World Health Assembly on 20 May 2025 was a landmark moment in global health.
An international study has, for the first time, revealed a strong and direct link between the rise of antibiotic-resistant bacteria and universal disinfection procedures applied to patients in intensive care units. Published in The Lancet Microbe, the study calls for a reassessment of health care guidelines on the widespread use of disinfectants.
Scientists from the A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a new artificial intelligence (AI)-based method called "Fragle" that makes tracking cancer easier and faster using blood tests.
Myelodysplastic syndromes (MDS) are a group of disorders that typically arise in adulthood, especially after the age of 70, and their five-year survival rate is around 30%. MDS are characterized by defective maturation of blood cells in the bone marrow, leading to a range of health problems such as fatigue and recurrent infections. Without appropriate treatment, they may progress to acute myeloid leukemia, a much more severe disease.
AI guidance for clinicians aimed at reducing the spread of Clostridioides difficile—a bacteria that can be deadly for sick patients—was deployed for the first time in a hospital setting, according to a University of Michigan-led study published in JAMA Network Open.
Women with breast cancer who were also carriers of the BRCA1 or BRCA2 mutation and received textured breast implants as part of their reconstructive surgery after mastectomy were 16 times more likely to develop breast-implant-associated anaplastic large cell lymphoma (BIA-ALCL), a rare T-cell lymphoma, compared to similar women without these genetic mutations, according to a study published today in Blood Advances.