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UK study evaluates effectiveness of cancer diagnosis pathway for patients with non-specific symptoms

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  • 2025-09-11 00:25 event
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UK study evaluates effectiveness of cancer diagnosis pathway for patients with non-specific symptoms
A major UK study has provided the most comprehensive analysis to date of a cancer diagnosis pathway for patients presenting with non-specific symptoms (NSS), such as unexplained weight loss or fatigue. These symptoms can indicate a wide range of conditions, from benign diseases to late-stage cancers, making timely and accurate diagnosis a significant challenge in primary care.

575. Microplastic exposure linked to Alzheimer's disease in mice with APOE4 gene

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Micro- and nanoplastics prevalent in the environment routinely enter the human body through the water we drink, foods we eat, and even the air we breathe. Those plastic particles infiltrate all systems of the body, including the brain, where they can accumulate and trigger Alzheimer's-like conditions, according to a new study by researchers in the University of Rhode Island College of Pharmacy.

576. Chronic alcohol use halts liver cell regeneration, new study finds

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Excessive alcohol consumption can disrupt the liver's unique regenerative abilities by trapping cells in limbo between their functional and regenerative states, even after a patient stops drinking, researchers at University of Illinois Urbana-Champaign and collaborators at Duke University and the Chan Zuckerberg Biohub Chicago describe in a new study.

577. Smartwatches detect early signs of PTSD among those watching coverage of the Oct. 7 attacks in Israel

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In a three‐year study involving more than 5,000 residents of Israel before and after the mass traumatic events of October 7, 2023, those who watched extensive media coverage of the attacks were found to be more likely to develop post‐traumatic stress disorder (PTSD).

578. A 'universal' therapy against the seasonal flu? Antibody cocktail targets virus weak spot

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An unusual therapy developed at The Jackson Laboratory (JAX) could change the way the world fights influenza, one of the deadliest infectious diseases. In a new study in Science Advances, researchers report that a cocktail of antibodies protected mice—including those with weakened immune systems—from nearly every strain of influenza tested, including avian and swine variants that pose pandemic threats.

579. Traditional and 'existential' wellness vary significantly among US regions

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Northeastern and Midwestern residents tend to have higher physical, social, and financial—i.e., "traditional"—wellness, while Southern residents have higher "existential" wellness, involving a sense of purpose and community identity, per an analysis of survey data from more than 325,000 U.S. residents.

580. Soft robot intubation device, designed specifically for non-expert users, could save lives

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Maintaining an open airway is a critical priority in emergency medicine. Without the flow of oxygen, other emergency interventions can become ineffective at saving the patient's life. However, creating this airway through endotracheal intubation is a difficult task for highly trained individuals and under the best of circumstances.

581. Study reveals how menopause impacts women's voices, and why it matters

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A new University of South Florida study published in Menopause highlights a largely overlooked health issue: voice changes that many women experience during menopause, often triggered by falling levels of estrogen and progesterone.

582. Missing Y gene linked to male infertility

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University of Hawaiʻi at Mānoa scientists have uncovered a direct link between a missing Y chromosome gene and male infertility. Their new research reveals that deleting this single gene in mice not only caused infertility but also disrupted hundreds of other genes vital for healthy sperm. The findings, published in Cell Death & Differentiation, offer significant implications for understanding reproductive health.

583. Veteran recovery programs show 41% death risk reduction through incentive system

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The chance to win a few dollars every time they pass a drug test, and the possibility of bigger prizes the longer they stay off drugs like methamphetamine and cocaine, may be enough to keep veterans from dying as they navigate early recovery, a new study suggests.

584. UK study evaluates effectiveness of cancer diagnosis pathway for patients with non-specific symptoms

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A major UK study has provided the most comprehensive analysis to date of a cancer diagnosis pathway for patients presenting with non-specific symptoms (NSS), such as unexplained weight loss or fatigue. These symptoms can indicate a wide range of conditions, from benign diseases to late-stage cancers, making timely and accurate diagnosis a significant challenge in primary care.

585. Stowaway rat on transatlantic flight reveals hidden global health risks

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In 2017, a flight from Miami to Berlin took a surprising turn when passengers discovered a rat on board. After landing, it was captured and handed over to the Friedrich-Loeffler-Institut (FLI). There, it was not only seen as a nuisance, but also as an opportunity to examine it as a possible carrier of pathogens.

586. Timely opioid administration cuts hospitalizations for pediatric sickle cell crises

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Providing timely pain relief may reduce chances of hospitalization for children presenting to the emergency department with a sickle cell crisis, according to a study published online Sept. 2 in JAMA Pediatrics.

587. Invasive Asian longhorned tick confirmed in Maine for the first time

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An invasive species of tick has been confirmed in Maine for the first time, marking the farthest northeast detection of the pest in the United States.

588. Protein found in the eye and blood significantly associated with cognition scores

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Neurocognitive impairments are classified by pathological changes with potential for destruction of neural tissue. One change known to occur in neurodegenerative disorders is an accumulation of proteins causing pathological damage.

589. Poor cardiovascular-kidney-metabolic health increases psoriasis risk

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Poor cardiovascular-kidney-metabolic (CKM) health is associated with an increased risk for psoriasis, especially for those with high genetic risk, according to a study published online July 18 in the Journal of the European Academy of Dermatology and Venereology.

590. Repurposing a diabetes medication to prime CAR T cancer targets

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Urothelial carcinoma (UC) is the second most common genitourinary cancer, leading to over 16,000 deaths a year in the United States. Despite recent advances, the 5-year survival rate for metastatic UC remains about 5% to 10%.

591. Focusing on children's first 1,001 days can build neighborhood support for migrant families

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The UK government's new ten-year health plan for England prioritizes tackling health inequalities through local preventive measures. One promising approach is to build on the strengths of migrant families by fostering neighborhood peer support—particularly for underserved communities.

592. Novel biomarkers may help improve cardiovascular disease risk prediction

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Scientists have discovered more than 100 new epigenetic biomarkers that may help predict cardiovascular disease risk and inform preventive care measures to improve long-term outcomes, according to a recent study published in Circulation.

593. Researchers keep a mammalian cochlea alive outside the body for the first time

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Shortly before his death in August 2025, A. James Hudspeth and his team in the Laboratory of Sensory Neuroscience at The Rockefeller University achieved a groundbreaking technological advancement: the ability to keep a tiny sliver of the cochlea alive and functional outside of the body for the first time. Their new device allowed them to capture the live biomechanics of the cochlea's remarkable auditory powers, including exceptional sensitivity, sharp frequency tuning, and the ability to encode a broad range of sound intensities.

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