Unlocking the secrets of gene therapy delivery: New insights into genome ejection from AAV vectors

University of Michigan researchers have uncovered new details of the process that HIV uses to hijack cells' transportation systems for its own survival.

Wildfires might inadvertently increase the risk of flu and COVID-19 outbreaks, a new study argues.

A significant opportunity to increase women's access to the most effective form of contraception and abortion care is being missed in Australia, according to new research from Monash University's SPHERE Center of Research Excellence.

The gut microbiome and the metabolites it produces offer promising insight into disease severity in critically ill patients. In a collaborative effort, researchers from the U.S. and the Netherlands developed the metabolic dysbiosis score (MDS), a novel biomarker index based on the levels of 13 key fecal metabolites—the chemical byproducts of digestion. The designed index can identify high-risk patients early and guide timely interventions that could save the lives of critically ill hospitalized patients.

Kennedy researchers have uncovered key design parameters for bispecific T-cell engagers (TcEs)—a class of cancer immunotherapy drugs. The findings may help unlock the full potential of TcEs and revolutionize cancer treatment for patients.

Winter is here, along with cold days and the inevitable seasonal surge in respiratory viruses.

What happens on the skin often begins much deeper. In women living with chronic inflammation, pain, and recurrent skin lesions, the root of the problem may be linked to hormonal, immune, and metabolic imbalances.

For centuries, humans have searched for ways to extend life. Alchemists never found the philosopher's stone, but scientists have consistently shown that a longer life can be attained by eating less—at least in certain lab animals. But can we find a way to live longer while still enjoying our food?

The human brain is made up of billions of interconnected cells that are constantly talking to each other. A new study published in Nature zooms in to the single-cell level to see how this cellular communication may be going wrong in brains affected by post-traumatic stress disorder (PTSD).

Watching a baby babble, play and interact with others can provide useful insight into what their cognitive ability might be like decades later, according to new University of Colorado Boulder research published in the journal PNAS.

A straightforward nightly activity may act as a memory-boosting tool, a new study has revealed.

Understanding how people visually browse their surroundings and direct their gaze in specific situations is a long-standing goal among psychology researchers. Past studies suggest that humans exhibit oculomotor biases, which are tendencies that guide the way they look at the world around them, for instance, preferentially directing their gaze around the center of what they are visually exposed to at a given time.

A review published in Health Affairs Scholar highlights significant limitations in the existing evidence base for perinatal palliative care (PPC) in the United States, raising concerns about its capacity to adequately support a growing, vulnerable patient population increasingly directed towards it due to abortion restrictions.

19 June 2025, Cairo, Egypt – Substance use across the Eastern Mediterranean Region is growing among vulnerable groups, including migrants and displaced persons. This silent crisis, taking place in the shadow of conflict, displacement, marginalization and economic hardship, is compounded by the loss of social support networks. In 2022, 6.7% of people aged between 15 and 64 in the Region had used drugs, surpassing the global average. Young men are particularly affected, with nearly 5% reporting cannabis use in the past year. The treatment gap is particularly alarming. Only 1 in 13 people with substance use disorders receive care. Substance use contributes to the spread of infectious diseases like HIV, hepatitis and tuberculosis. It takes a heavy toll on mental health, community safety and national economies. In some countries, the economic impact has reached 2% of gross domestic product. Recognizing the gravity of the situation, on 1 June 2025 the Regional Health Alliance (RHA), which brings together 18 UN agencies, led by the World Health Organization (WHO), to facilitate multilateral engagement and joint efforts to address health priorities, convened a regional technical meeting to strengthen coordination, explore joint interventions and align the response to substance use with the complex realities on the ground. Under the leadership of WHO’s Read more...

In moments of acute pain, physical trauma and psychological distress, every minute spent in a hospital emergency department (ED) waiting room can seem like a lifetime. But what happens when the language barrier prevents triage staff from properly understanding patients' medical conditions?

Exposure to wildfire smoke and heat stress can negatively affect birth outcomes for women, especially in climate-vulnerable neighborhoods, according to a recent study led by USC postdoctoral researcher Roxana Khalili, Ph.D.

Brain networks responsible for sensing, understanding, and responding emotionally to pain develop at different rates in infants, with the conscious understanding of pain not fully developed until after birth, finds a new study led by UCL (University College London) researchers.

For many, fitness trackers have become indispensable tools for monitoring how many calories they've burned in a day. But for those living with obesity, who are known to exhibit differences in walking gait, speed, energy burned and more, these devices often inaccurately measure activity—until now.