When B-cells turn cancerous may decide fate of childhood leukemia treatment

A new study by UCLA researchers shows that removing a modest $45 out-of-pocket fee significantly improved access to digital breast tomosynthesis (3D mammography), an advanced breast cancer screening technology. Researchers found that eliminating the fee increased overall usage by several percentage points and particularly benefited underserved patient populations, including racial and ethnic minorities and non-English speakers. The study appears in the Journal of the American College of Radiology.

Blood cancer patients who may have previously struggled to find a donor for transplantation now have more options. A new study shows that patients achieve good outcomes with a partial match drawn from the national public registry of donors when they are treated with the immune-suppressing drug cyclophosphamide. Survival rates at one year were on par with rates seen in other studies with fully matched donors.

A new update, led by researchers at the UNC School of Medicine and the Gillings School of Global Public Health, describes major findings from the past half decade in the realm of psychiatric genomics and next steps for researchers.

Van Andel Institute scientists and collaborators have discovered a potential treatment target that may re-energize dysfunctional or "exhausted" immune cells in their fight against cancer.

A simple saliva test could transform the lives of millions of children and adults worldwide who are on the keto diet to manage their epilepsy, and who currently endure uncomfortable finger prick tests.

A new study from the University of Michigan Rogel Health Cancer Center, published in Science, sheds light on how two distinct classes of mutations in the FOXA1 gene—commonly altered in prostate cancer—drive tumor initiation formation and therapeutic resistance.

Tarang Parekh was getting ready for work at his apartment in Houston, Texas, in 2022, when he heard gunfire. He'd never heard the sound before, except on TV, but instantly recognized it. He ran downstairs and saw a gruesome scene. It wasn't something he ever expected to see where he lived.

Cedars-Sinai investigators have developed an investigational therapy that brought a significant number of patients with moderate to severe Crohn's disease into remission, according to a new study published in The Lancet Gastroenterology & Hepatology. The findings from the international Phase II-A study suggest that a monoclonal antibody targeting a protein called TL1A could offer a new treatment option for patients with the disease.

Researchers at the University Medical Center Göttingen (UMG) have shown how a minimal change in a single ion channel increases the sensitivity of sensory cells in the inner ear. Even soft sounds, such as a whisper, are perceived more clearly, but can cause prolonged overloading, which can ultimately lead to long-term hearing loss. These findings deepen our understanding of how sound information is encoded in the ear. The results have been published in the journal Science Advances.

Depression affects 1–2% of children younger than 13 in the U.S. and can arise as early as age 3, but a specialized therapeutic intervention can help preschool-aged children find relief from this condition—with benefits lasting at least four years, according to a new study led by researchers at Washington University School of Medicine in St. Louis.

An eight-year HonorHealth Research Institute clinical trial, using non-surgical techniques, showed 86% of patients with a type of usually fatal low blood pressure known as "structural shock" survived at least three months, while 73% survived at least six months, according to a study presented at a major heart convention.

A new tool—seen as the Google Earth for genomics—will transform how scientists visualize and analyze genomic data, advancing cancer research techniques.

Low-grade serous ovarian cancer (LGSC), accounts for just 5% to 10% of all epithelial ovarian cancers, but its distinct biology makes it especially challenging to treat. While the origin of this disease has not been identified, a multitude of patients are initially diagnosed with non-invasive lesions, or so-called Serous Borderline Tumors.

A person's capacity for attention has a profound impact on what they see, dictating which details they glean from the world around them. As they walk down a busy street, the focus of their attention may shift to a compelling new billboard advertisement or a shiny Lamborghini parked on the curb.

Over the past decades, some lawyers have started using brain imaging scans as evidence during criminal trials, to provide a possible explanation for the criminal behavior of defendants. This was justified by recent neuroscientific studies, which found that some people who commit crimes present differences in specific parts of the brain. Yet a key question remains: are these brain changes causal, compensatory or incidental to the behavior?

DEAR MAYO CLINIC: My back's been bothering me, and everyone seems to have ideas what's causing the pain. Can you help?

Five people who are incarcerated at a New Mexico county detention facility have measles, the state health department said Thursday.

Current tuberculosis infection tests struggle to detect the disease in those with HIV. A common co-infection, HIV can hide TB from traditional tests by eliminating the immune cells relied upon to sound the alarm.