When healing turns harmful: Adrenal support cells tied to cancer origin

An alliance of scientists at the Broad Institute and Bayer Pharmaceuticals have developed a drug candidate, sevabertinib, that could be a new treatment for a group of lung cancer patients who have few options today.

In recent research, treatment with osimertinib plus a platinum–pemetrexed chemotherapy combination resulted in statistically significant and clinically meaningful improvement in overall survival in patients with newly diagnosed EGFR-mutated advanced non-small cell lung cancer (NSCLC) compared to osimertinib alone.

An out-of-state visitor with a confirmed case of measles may have exposed people at a southern Colorado hotel and gas station earlier this week, according to state and Huerfano County health officials.

Studies have found that the density of tobacco retailers in a neighborhood is associated with smoking, the leading cause of preventable disease and death. But what if smokers and policymakers were able to understand the impact of this exposure not just on a population level but at the individual level? Rather than relying on longer recall periods and assumptions about how people move through their neighborhoods, as many studies do, what if researchers could follow the movements and behaviors of smokers more naturally—hour by hour, day by day?

A newly formed, multistate coalition represents the largest coordinated pushback to federal public health guidance under Health Secretary Robert F. Kennedy Jr. to date.

Volleyball player Madelyn Olympia, 14, started experiencing back pain after diving for a ball.

It's no surprise to Northeastern food policy expert Darin Detwiler that high levels of lead are being found in both protein powders and bottles of cinnamon.

A new study led by researchers at McMaster University reveals that hidden fat deep inside the abdomen and liver may quietly damage arteries, even in people who appear healthy.

Former UK prime minister Rishi Sunak has called for a targeted prostate cancer screening program for men most at high risk of the disease, reviving a national debate on how to save more lives and tackle health inequalities among men.

New research suggests a missing brain molecule may hold the key to understanding—and potentially treating—the faulty neural circuits seen in Down syndrome. Restoring the molecule, called pleiotrophin, could enhance brain function in people with Down syndrome and other neurological diseases, even in adulthood, researchers say.

Women who receive more virtual antenatal care during their second or third trimesters could experience poorer pregnancy outcomes, including higher risks of preterm birth, cesarean sections and neonatal intensive care unit admissions, a new study suggests.

A new study led by Yale School of Medicine's Department of Orthopedics & Rehabilitation unveiled key insights into the knee joint's vulnerability for young athletes who suffer anterior cruciate ligament (ACL) injuries combined with medial meniscus tears.

As LGBTQ+ youth across the U.S. continue to face higher rates of mental health challenges and substance use, community-based organizations (CBOs) are playing an increasingly vital role in providing safe, supportive spaces. Yet, despite their growing importance, these organizations remain largely understudied.

Large language models (LLMs) can store and recall vast quantities of medical information, but their ability to process this information in rational ways remains variable. A new study led by investigators from Mass General Brigham demonstrated a vulnerability in that LLMs are designed to be sycophantic, or excessively helpful and agreeable, which leads them to overwhelmingly fail to appropriately challenge illogical medical queries despite possessing the information necessary to do so.

Pulmonary fibrosis is a deadly disease in which the lungs become thickened and scarred, gradually losing their ability to deliver oxygen to the body. Now, scientists at UC San Francisco have identified a key cellular switch that drives this process—and found a way to block it in mice.

The Food and Drug Administration on Thursday announced the first round of experimental drugs that will receive drastically expedited reviews at the agency, part of an effort to prioritize medicines the Trump administration deems as "supporting U.S. national interests."

Two Californians diagnosed with mpox may be the first U.S. cases resulting from the local spread of a different version of the virus, health officials said.

The idea that building better health care systems can improve and save people's lives may seem obvious, but until now there has been little published with the data and statistical muscle to prove it.