X-ray and radar technology combined to reduce cancer screening risks

Researchers have discovered a protein which is critical for steering melanoma cancer cells as they spread throughout the body. The malignant cells become dependent on this protein to migrate, pointing to new strategies for impeding metastasis.

Rheumatoid arthritis (RA) is a chronic autoimmune disease in which the immune system mistakenly attacks the lining of the joints (the synovium), causing pain, swelling, and progressive damage. Approximately 18 million people worldwide live with RA. Early diagnosis and treatment can relieve symptoms, slow disease progression, and help prevent disability.

For patients with eosinophilic granulomatosis with polyangiitis (EGPA), rituximab is not superior to the conventional remission induction strategy, according to a study published online July 29 in the Annals of Internal Medicine.

People with diabetes suffer from depression more frequently than average. Researchers from the German Diabetes Center (DDZ), the Research Institute of the Diabetes Academy Mergentheim (Forschungsinstitut an der Diabetes Akademie Mergentheim, FIDAM) and the German Center for Diabetes Research (DZD) were able to show in a large-scale analysis that biomarkers for chronic inflammation levels influence the therapeutic success of depressive symptoms—however, with considerable differences in type 1 and type 2 diabetes. The findings could help to customize the treatment of depression in people with diabetes in the future.

President Donald Trump has introduced a new effort to help Americans more easily share their health records with doctors, using new technology and artificial intelligence (AI) tools.

The earliest warning signs of multiple sclerosis (MS) may emerge more than a decade before the first classical neurological symptoms occur, according to new research from the University of British Columbia.

A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in T-cell development and function.

Medicare drug plans are increasingly excluding coverage of new specialty drugs that treat complex conditions like cancers and autoimmune diseases. New research from the USC Schaeffer Center shows how these barriers may come at a cost to patients' health.

A sudden surge of chikungunya cases has been reported in Foshan city in China, increasing from 478 cases to almost 3,000 cases within a week, according to South China Morning Post.

A new radioimmunotherapy approach has been shown to successfully eliminate cancer stem cells (CSCs) in preclinical models of ovarian cancer, outperforming the current gold standard. This research, published in the July issue of The Journal of Nuclear Medicine, lays the foundation for further development of radionuclide therapies targeting CSCs, offering renewed hope for more effective treatment options and improved outcomes for patients.

A new Stanford-led study sheds light on "an emerging psychological health crisis" that disproportionately affects girls. Published July 30 in The Lancet Planetary Health, the study is among the first to quantify how repeated climate stressors impact the psychological well-being and future outlook of adolescents in low-resource settings.

Intestinal bacteria are important for human health as they help digest food and regulate immune function. Thus, in recent years, it has become clear that gut microbiota dysbiosis, an imbalance in types and composition of intestinal bacteria, is associated with digestive disorders and other diseases. However, the mechanism by which bacteria interact in the intestine to maintain the microbiota balance remains unclear.

About one quarter of patients with muscle-invasive bladder cancer (MIBC) may be treated and derive a benefit with the current standard chemotherapy. To better understand why some tumors resist chemotherapy and identify better ways to treat those cancers, researchers at Baylor College of Medicine have conducted a detailed molecular analysis of MIBC tumors. The results, published in Cell Reports Medicine, offer potential new ways to identify which patients will benefit from chemotherapy and reveal possible new treatment strategies.

Males born in summer months reported higher depression symptom scores than males born during other seasons, according to a study from Kwantlen Polytechnic University. Anxiety symptoms showed no association with season of birth for either sex.

It's a cold, crisp evening and the air carries a chill that bites. As temperatures drop and houses get colder, we turn to trusted sources of warmth such as wood fires, heaters, hot water bottles and warm drinks.

Without even realizing it, your world sometimes gradually gets smaller: less walking, fewer days in the office, canceling on friends. Watching plans disintegrate on the chat as friends struggle to settle on a date or place for a catch-up.

Heart attacks remain a leading cause of death and disability worldwide. The permanent loss of heart muscle cells—known as cardiomyocytes—and the heart's limited regenerative capacity often lead to chronic heart failure. Current treatment strategies manage symptoms but do not repair the underlying damage.

In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune system's most powerful cancer-killing agents. This approach suggests a new way to deliver immunotherapy, acting as an internal factory that produces tumor-targeting immune cells over time and potentially offering longer-lasting protection.