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Two molecular targets—human epidermal growth factor 2 (HER2) and cluster of differentiation 24 (CD24)—are highly promising candidates for new nuclear diagnostics and therapeutics for endometrial cancer, according to new research published in The Journal of Nuclear Medicine.
A comprehensive study led by researchers from the A*STAR Institute for Human Development and Potential (A*STAR IHDP) has found that more than 1 in 4 healthy-weight Chinese women in their 20s and 30s already have low muscle mass and weaker bones—hidden risks for fractures and metabolic diseases that standard BMI measurements cannot identify.
Immune-checkpoint therapy (ICT), which attempts to harness a patient's own immune system to fight cancer, has revolutionized cancer care over the past two decades. However, many patients do not respond to this therapy, and drug resistance due to immune-evasive (or "cold") tumors remains poorly understood.
Vanderbilt researchers, including those from the Vanderbilt Brain Institute, have made significant strides in understanding how the enteric nervous system—sometimes called the "brain" of the gut—forms and functions.
The first tool designed to understand why young video gamers purchase loot boxes—digital items in games that offer random rewards after purchase—could potentially help identify early signs of gaming-related harms, researchers have said.
A single dose of LSD eased anxiety symptoms for many folks and the benefits lasted up to three months, a new study reports.
A pizza shop with 30 delivery people ought to be able to deliver a lot of pizzas—if their cars don't break down on the way. Likewise, genes that produce a lot of messenger RNA (mRNA) molecules can build a lot of proteins—if these molecules don't fall apart before the job gets done.
Despite vaccines and treatments, SARS-CoV-2—the virus that causes COVID-19—continues to pose a global health threat, driven by new variants and its ability to hijack human cells in ways that still aren't fully understood. Now, scientists at Scripps Research have pinpointed dozens of human proteins that SARS-CoV-2 needs to complete its full life cycle, from entering a cell to replicating and releasing new viral particles.
When hospitalized patients struggle to breathe, doctors typically reach for their stethoscopes, but results from a Rutgers and RWJBarnabas Health clinical study in JAMA Network Open suggest they should diagnose the problem with portable ultrasounds instead.
Scientists have developed a tool made from a modified glue gun that can 3D print bone grafts directly onto fractures and defects during surgery.
Bladder cancer is a painful and often recurring disease, not just for humans, but for our canine companions as well. Urothelial carcinoma, the most common type of bladder cancer, affects both species in remarkably similar ways—from the genetics to the clinical progression. This shared burden also means a shared challenge: how to detect and treat the aggressive form of the disease that's responsible for most relapses.
More than one billion people are living with mental health disorders, according to new data released by the World Health Organization (WHO), with conditions such as anxiety and depression inflicting immense human and economic tolls. While many countries have bolstered their mental health policies and programs, greater investment and action are needed globally to scale up services to protect and promote people's mental health.
As we get older, our muscle strength slowly declines—increasing our risk of falls, injuries, and loss of independence. In particular, we rely on our lower body strength for many essential daily activities such as walking and climbing stairs. Strength training can help offset the weakening of muscles, but not everyone has the means (or even the desire) to hit the gym for regular weightlifting sessions.
From Pong and Pac-Man to Minecraft and Fortnite, video games have always been a lot of fun. Sometimes, however, gamers become fixated, compulsive or—worse—spiral into a full-blown gaming disorder marked by isolation, distress, interpersonal conflicts and severe neglect of responsibilities. But are the games to blame?
From images of fruit to claims of being "sugar-free," baby foods often feature misleading claims aimed at convincing parents the products are a healthy choice, new research shows.
Big pharmacies and public health clinics in Georgia are not yet giving this year's COVID-19 booster shots, or are putting new restrictions in place, amid vaccine uncertainty under Department of Health and Human Services Secretary Robert F. Kennedy.
The Trump administration has given notice that political appointees, rather than scientists, will ultimately decide who gets grant money from the world's largest biomedical research funder—the federal government's National Institutes of Health.
Fibrosis of the lungs is often a silent disease until it's too late. By the time patients are diagnosed, the scarring of their lung tissue is already advanced, and current treatments offer little more than a slowing of the inevitable. But what if we could understand the very first steps of this disease before irreversible damage sets in?
The addition of the hormone progesterone to gender-affirming hormone therapy leads to increased breast growth for transgender people following feminizing hormone therapy. This is demonstrated by an Amsterdam UMC-led trial among 90 participants and these results were presented at the European Professional Association for Transgender Health (EPATH) annual congress in Hamburg.