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Only forty-two percent of youths with sickle cell disease (SCD) received dental services in 2022, according to a research letter published online Sept. 3 in JAMA Network Open.
Over 5% of children and adolescents are diagnosed with attention deficit/hyperactivity disorder (ADHD) globally. This condition is characterized by a short attention span, hyperactivity or impulsive behavior that is age-inappropriate, making it difficult for patients to navigate interpersonal relationships, the formal education system, and social life.
Late-onset Alzheimer's disease (LOAD) is the most common form of dementia, with symptoms appearing after age 65. Since carriers of clusterin risk alleles have an increased likelihood of developing LOAD, the associated clusterin protein is of interest to researchers. In order to better understand the function of the associated protein, researchers at the Max Planck Institute of Biochemistry have deciphered the molecular basis for the chaperone function of clusterin.
Sepsis arises from infection and immune dysregulation. Neutrophils play a key role in its progression, yet existing clinical tools cannot simultaneously isolate these cells and measure their functional activity.
Cellphones are everywhere, including in the hands of homeless people, a population among America's sickest—average life expectancy is just 51—and among the hardest to reach by health care workers.
Compared with dual antiplatelet therapy (DAPT), a de-escalated DAPT strategy resulted in similar graft occlusion rates and reduced clinically relevant bleeding in patients who underwent coronary artery bypass grafting (CABG), according to late-breaking research presented in a Hot Line session Sept. 1 at ESC Congress 2025, held in Madrid.
Anita Paulsen is a nurse and sexologist. She recently defended her doctoral thesis on sexual health communication after gynecological cancer. Through her work and research, she has met many cancer survivors who miss the intimacy in their lives.
Two molecular targets—human epidermal growth factor 2 (HER2) and cluster of differentiation 24 (CD24)—are highly promising candidates for new nuclear diagnostics and therapeutics for endometrial cancer, according to new research published in The Journal of Nuclear Medicine.
A comprehensive study led by researchers from the A*STAR Institute for Human Development and Potential (A*STAR IHDP) has found that more than 1 in 4 healthy-weight Chinese women in their 20s and 30s already have low muscle mass and weaker bones—hidden risks for fractures and metabolic diseases that standard BMI measurements cannot identify.
Immune-checkpoint therapy (ICT), which attempts to harness a patient's own immune system to fight cancer, has revolutionized cancer care over the past two decades. However, many patients do not respond to this therapy, and drug resistance due to immune-evasive (or "cold") tumors remains poorly understood.
Vanderbilt researchers, including those from the Vanderbilt Brain Institute, have made significant strides in understanding how the enteric nervous system—sometimes called the "brain" of the gut—forms and functions.
The first tool designed to understand why young video gamers purchase loot boxes—digital items in games that offer random rewards after purchase—could potentially help identify early signs of gaming-related harms, researchers have said.
A single dose of LSD eased anxiety symptoms for many folks and the benefits lasted up to three months, a new study reports.
A pizza shop with 30 delivery people ought to be able to deliver a lot of pizzas—if their cars don't break down on the way. Likewise, genes that produce a lot of messenger RNA (mRNA) molecules can build a lot of proteins—if these molecules don't fall apart before the job gets done.
Despite vaccines and treatments, SARS-CoV-2—the virus that causes COVID-19—continues to pose a global health threat, driven by new variants and its ability to hijack human cells in ways that still aren't fully understood. Now, scientists at Scripps Research have pinpointed dozens of human proteins that SARS-CoV-2 needs to complete its full life cycle, from entering a cell to replicating and releasing new viral particles.
When hospitalized patients struggle to breathe, doctors typically reach for their stethoscopes, but results from a Rutgers and RWJBarnabas Health clinical study in JAMA Network Open suggest they should diagnose the problem with portable ultrasounds instead.
Scientists have developed a tool made from a modified glue gun that can 3D print bone grafts directly onto fractures and defects during surgery.
Bladder cancer is a painful and often recurring disease, not just for humans, but for our canine companions as well. Urothelial carcinoma, the most common type of bladder cancer, affects both species in remarkably similar ways—from the genetics to the clinical progression. This shared burden also means a shared challenge: how to detect and treat the aggressive form of the disease that's responsible for most relapses.
More than one billion people are living with mental health disorders, according to new data released by the World Health Organization (WHO), with conditions such as anxiety and depression inflicting immense human and economic tolls. While many countries have bolstered their mental health policies and programs, greater investment and action are needed globally to scale up services to protect and promote people's mental health.