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How quickly mRNA degrades is linked to autoimmune disease risk

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  • 2025-09-05 22:39 event
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How quickly mRNA degrades is linked to autoimmune disease risk
A pizza shop with 30 delivery people ought to be able to deliver a lot of pizzas—if their cars don't break down on the way. Likewise, genes that produce a lot of messenger RNA (mRNA) molecules can build a lot of proteins—if these molecules don't fall apart before the job gets done.

868. Q&A: Delivering health care to hard-to-reach population via telehealth

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Cellphones are everywhere, including in the hands of homeless people, a population among America's sickest—average life expectancy is just 51—and among the hardest to reach by health care workers.

869. De-escalation of dual antiplatelet therapy provides benefits in patients after coronary artery bypass grafting

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Compared with dual antiplatelet therapy (DAPT), a de-escalated DAPT strategy resulted in similar graft occlusion rates and reduced clinically relevant bleeding in patients who underwent coronary artery bypass grafting (CABG), according to late-breaking research presented in a Hot Line session Sept. 1 at ESC Congress 2025, held in Madrid.

870. Why discussing sex is important for patients after treatment for gynecological cancer

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Anita Paulsen is a nurse and sexologist. She recently defended her doctoral thesis on sexual health communication after gynecological cancer. Through her work and research, she has met many cancer survivors who miss the intimacy in their lives.

871. New radiotheranostic targets identified for diagnosis and treatment of endometrial cancer

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Two molecular targets—human epidermal growth factor 2 (HER2) and cluster of differentiation 24 (CD24)—are highly promising candidates for new nuclear diagnostics and therapeutics for endometrial cancer, according to new research published in The Journal of Nuclear Medicine.

872. Singapore's young women have 'skinny-fat' risks typically seen in older age

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A comprehensive study led by researchers from the A*STAR Institute for Human Development and Potential (A*STAR IHDP) has found that more than 1 in 4 healthy-weight Chinese women in their 20s and 30s already have low muscle mass and weaker bones—hidden risks for fractures and metabolic diseases that standard BMI measurements cannot identify.

873. Cancer study identifies why patients do not respond to personalized immune therapy, sparking new vaccine

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Immune-checkpoint therapy (ICT), which attempts to harness a patient's own immune system to fight cancer, has revolutionized cancer care over the past two decades. However, many patients do not respond to this therapy, and drug resistance due to immune-evasive (or "cold") tumors remains poorly understood.

874. Researchers uncover critical genetic drivers of the gut's 'nervous system' development

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Vanderbilt researchers, including those from the Vanderbilt Brain Institute, have made significant strides in understanding how the enteric nervous system—sometimes called the "brain" of the gut—forms and functions.

875. Tool focused on understanding why young people buy video game loot boxes could help pinpoint gaming-related issues

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The first tool designed to understand why young video gamers purchase loot boxes—digital items in games that offer random rewards after purchase—could potentially help identify early signs of gaming-related harms, researchers have said.

876. LSD may ease anxiety symptoms for months, study finds

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A single dose of LSD eased anxiety symptoms for many folks and the benefits lasted up to three months, a new study reports.

877. How quickly mRNA degrades is linked to autoimmune disease risk

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A pizza shop with 30 delivery people ought to be able to deliver a lot of pizzas—if their cars don't break down on the way. Likewise, genes that produce a lot of messenger RNA (mRNA) molecules can build a lot of proteins—if these molecules don't fall apart before the job gets done.

878. Key human proteins that power coronavirus replication point to new treatment strategies

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Despite vaccines and treatments, SARS-CoV-2—the virus that causes COVID-19—continues to pose a global health threat, driven by new variants and its ability to hijack human cells in ways that still aren't fully understood. Now, scientists at Scripps Research have pinpointed dozens of human proteins that SARS-CoV-2 needs to complete its full life cycle, from entering a cell to replicating and releasing new viral particles.

879. Pocket ultrasound reduces hospital stays for patients with shortness of breath, study finds

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When hospitalized patients struggle to breathe, doctors typically reach for their stethoscopes, but results from a Rutgers and RWJBarnabas Health clinical study in JAMA Network Open suggest they should diagnose the problem with portable ultrasounds instead.

880. 3D printing 'glue gun' can generate bone grafts directly onto fractures

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Scientists have developed a tool made from a modified glue gun that can 3D print bone grafts directly onto fractures and defects during surgery.

881. Discovery of a new biomarker for early detection of bladder cancer in both dogs and humans

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Bladder cancer is a painful and often recurring disease, not just for humans, but for our canine companions as well. Urothelial carcinoma, the most common type of bladder cancer, affects both species in remarkably similar ways—from the genetics to the clinical progression. This shared burden also means a shared challenge: how to detect and treat the aggressive form of the disease that's responsible for most relapses.

882. Over one billion people are living with mental health issues

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More than one billion people are living with mental health disorders, according to new data released by the World Health Organization (WHO), with conditions such as anxiety and depression inflicting immense human and economic tolls. While many countries have bolstered their mental health policies and programs, greater investment and action are needed globally to scale up services to protect and promote people's mental health.

883. Traditional Japanese samurai daily behavior improves leg strength, could be key to better mobility for seniors

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As we get older, our muscle strength slowly declines—increasing our risk of falls, injuries, and loss of independence. In particular, we rely on our lower body strength for many essential daily activities such as walking and climbing stairs. Strength training can help offset the weakening of muscles, but not everyone has the means (or even the desire) to hit the gym for regular weightlifting sessions.

884. Video game addiction in teens likely stems from preexisting mental health issues

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From Pong and Pac-Man to Minecraft and Fortnite, video games have always been a lot of fun. Sometimes, however, gamers become fixated, compulsive or—worse—spiral into a full-blown gaming disorder marked by isolation, distress, interpersonal conflicts and severe neglect of responsibilities. But are the games to blame?

885. Claims on baby food fail to stack up

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From images of fruit to claims of being "sugar-free," baby foods often feature misleading claims aimed at convincing parents the products are a healthy choice, new research shows.

886. COVID-19 boosters halted in Georgia amid federal uncertainty

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Big pharmacies and public health clinics in Georgia are not yet giving this year's COVID-19 booster shots, or are putting new restrictions in place, amid vaccine uncertainty under Department of Health and Human Services Secretary Robert F. Kennedy.

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