At-home melanoma testing: Skin patch test works in mice

Breaking the link between prescription drug list prices and compensation to middlemen like pharmacy benefit managers (PBMs) could cut a significant portion of the U.S.'s annual drug tab, finds a new analysis from the USC Schaeffer Center for Health Policy & Economics.

For the first time, researchers at the Netherlands Institute for Neuroscience and Amsterdam UMC have identified what happens in neural networks deep within the brain during obsessive thoughts and compulsive behaviors. Using electrodes implanted in the brain, they observed how specific brain waves became active. These brain waves serve as a biomarker for obsessive-compulsive disorder (OCD) and are an important step towards more targeted treatments.

Researchers at Uppsala University have identified a promising therapeutic approach for the challenging blood cancer multiple myeloma. In a new preclinical study, they demonstrate that a dual treatment with drugs that inhibit epigenetic regulation reduces tumor growth and induces cancer cell death. The findings are published in the journal Blood Advances.

Titanium dioxide (TiO2) has been classified as a possible human carcinogen through inhalation since 2006. This nanomaterial was used as a food coloring and opacifying agent (E171) until it was banned for use in food as a precautionary measure in France in 2020 and by the European Union in 2022. However, it is still widely used in many everyday products (toothpaste, sunscreen, make-up, medications, plastic, paper, paint, etc.).

While the incidence of breast cancer is highest for white women, Black women are more likely to have early-onset or more aggressive subtypes of breast cancer, such as triple-negative breast cancer. Among women under 50, the disparity is even greater: young Black women have double the mortality rate of young white women.

A wearable technology developed by Technion Professor Hossam Haick and colleagues in China enables real-time, noninvasive tracking and optimized treatment for diabetic patients.

Investigators led by Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how the metabolism of mitochondria supports T-cell proliferation and also prevents T-cell exhaustion in cancer and chronic infection, according to recent findings published in Nature Immunology.

A study comparing the effects of SARS-CoV-2 infection in lean and obese primates found different long-term consequences of the virus depending on prior obesity and metabolic disease.

Researchers have harnessed the power of artificial intelligence to design a blueprint for building a vaccine that aims to teach the body's immune system to fight cancer.

Critical questions need addressing before any clinical use of in vitro gametogenesis (IVG), says a new report by a Lancaster University-based research project.

A discovery at Hudson Institute more than 20 years ago is still sparking new medical insights, with researchers at a major US University using it to uncover vital facts about sexually transmitted disease (STI).

Thanks to a new technique, neurosurgeons at UMC Utrecht have been able to watch the blood flow in brain tissue live during surgery for the first time. Together with researchers from Eindhoven University of Technology, they have developed a method that allows them to detect the risk of a stroke during surgery sooner—and potentially prevent it. The technique could also be useful for other types of operations, such as kidney transplants.

Despite being one of the most preventable and treatable cancers, colorectal cancer continues to claim more lives in Black communities than in any other racial group in the United States. Incidence and mortality rates remain about 20% and 30% higher for Black individuals compared with White individuals, making it a leading driver of racial health disparities.

People with severe mental health problems can find it more difficult to live healthy lifestyles.

In a pair of articles published in Lancet Gastroenterology & Hepatology, scientists lay out the case for why we should expand treatment recommendations for people with hepatitis B.

In the world's first comprehensive study to evaluate both the nutritional quality and environmental footprint of food served in health care institutions using detailed, food-level data, researchers assessed menus and food procurement data from two hospitals and three nursing homes of average size in Germany. These institutions' foodservice likely reflects that of many health care institutions in high-income countries.

Konstanz researchers identify an enzyme that plays a role in the migration of cells in our body—not only during normal tissue formation and wound healing, but also when tumor cells metastasize. This makes the enzyme an interesting candidate for potential future therapeutic approaches.

During a severe heart attack many heart muscle cells die and are replaced by scar tissue to stabilize the heart wall. Connective tissue cells, known as fibroblasts (FB), are the dominant cell type in scar tissue.