Best practice recommendations for clinical homologous recombination deficiency testing published

Vertical and horizontal relative peripheral refraction (RPR) are associated with faster axial length progression and higher risk of incident myopia, according to a study published online June 16 in the American Journal of Ophthalmology.

Autism spectrum disorders are complex neurodevelopmental conditions affecting about 1 in 100 children worldwide. Early diagnosis would allow timely intervention to improve the development and quality of life for children with autism. Scientists have identified over 200 genes associated with autism, but predicting the risk of developing autism based on genetic information is not straightforward.

The official results of the BRACELET-01 (PrECOG 0113) trial have been published in Clinical Cancer Research, detailing the safety and efficacy of pelareorep, an investigational oncolytic virus immunotherapy, when added to paclitaxel chemotherapy, both with and without the checkpoint inhibitor avelumab.

Dozens of people in northeastern England have developed a rare and dangerous illness after receiving Botox injections, according to health officials in the U.K.

Investigators have unveiled for the first time that changes in certain genes affect an aggressive cancer, T-cell acute lymphoblastic leukemia (T-ALL), differently depending on genetic ancestry.

New research has found that the endothelial cell-specific A disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) regulates abnormal blood vessel growth in the damaged retina, which can cause vision loss or impairment.

Researchers at VCU Massey Comprehensive Cancer Center and the VCU Institute of Molecular Medicine (VIMM) have discovered a new and potentially revolutionary way to treat glioblastoma (GBM), the most aggressive type of brain cancer, which currently has no curative treatment options.

Colorectal cancer (CRC) is the second most common cause of death from cancer in the US and the most prevalent malignant tumor worldwide. CRC refers to cancer in the colon or rectum, the two parts that make up the large intestine. In the US, deaths from CRC in people under 55 have been increasing since the mid-2000s, highlighting the need for effective treatments.

Burned-out primary care physicians are increasingly seeking safe haven in concierge care and other free-market models of practice. This has resulted in an exodus from traditional primary care practices and exacerbated an already acute shortage of primary care physicians. These alternative models also give patients more personalized care and attention. But for the rest of people who get their primary care from traditional practices, the already pressing shortage of primary care doctors often gets worse.

Has your skin ever felt tight and dry after coming out of the ocean? You're not just imagining it. Scientists from Binghamton University, State University of New York have confirmed what beachgoers have felt for years—salt water dries out your skin—and why it happens.

Omega-3 fatty acids, popularly believed to reduce inflammation in the body, appear to increase certain inflammatory markers, researchers have found.

The newly launched South African Blood Regulatory (SABR) dataset reveals how genetic variation influences blood traits and gene activity in African populations, providing crucial insights into diseases like diabetes and heart disease.

UCLA scientists have uncovered a surprising survival strategy in cells, especially cancer cells, that may help explain how they adapt and keep growing even when nutrients are scarce and under metabolic stress. Their findings are published in Cancer & Metabolism.

In a paper published in the journal Nature Communications, biomedical engineers have shown how two brain regions quickly adapt to shift focus from one planned destination to another.

Researchers at the University of Georgia's Center for Tropical and Emerging Global Diseases have developed the first test to determine whether treatment for Chagas disease was effective. The study is published in the journal eLife.

A comprehensive carcinogenicity study on the world's most used herbicide, glyphosate, involving scientists from Europe and the U.S., has found that low doses of the controversial weed killer cause multiple types of cancer in rats.

Education, body mass index (BMI), and hypertension play a role in the spread of tau tangles, a hallmark of Alzheimer's disease, according to longitudinal PET imaging data presented at the 2025 Society of Nuclear Medicine and Molecular Imaging Annual Meeting. For patients, timely modification of these risk factors could slow down disease progression. The abstract was published in the Journal of Nuclear Medicine.

The number of women using medicinal cannabis is growing in New Zealand and overseas. They use cannabis treatment for general conditions such as pain, anxiety, inflammation and nausea, as well as gynecological conditions, including endometriosis, pelvic floor conditions, and menopause.