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Cell therapy improves overall survival of patients with colorectal cancer, study finds

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  • 2025-06-25 02:40 event
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Cell therapy improves overall survival of patients with colorectal cancer, study finds
Colorectal cancer (CRC) is the second most common cause of death from cancer in the US and the most prevalent malignant tumor worldwide. CRC refers to cancer in the colon or rectum, the two parts that make up the large intestine. In the US, deaths from CRC in people under 55 have been increasing since the mid-2000s, highlighting the need for effective treatments.

3.096. AI helps to detect dangerous colon polyps

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Colorectal cancer is one of the most common types of cancer in Europe, but timely screening can be highly effective in preventing it. Colonoscopy is considered the gold standard for this purpose. It enables potentially dangerous colon polyps to be detected and removed at an early stage. However, accurately distinguishing between benign and potentially malignant polyps requires significant expertise.

3.097. Novel PET imaging approach detects heart damage in patients with non-ischemic cardiomyopathy

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A new PET/CT imaging technique that visualizes activated fibroblasts in the heart muscle enables early detection of multiple forms of cardiomyopathy, according to research presented at the Society of Nuclear Medicine and Molecular Imaging 2025 Annual Meeting. By targeting fibroblast activation—an early indicator of myocardial fibrosis—this method provides valuable insights into disease progression and helps improve risk stratification for patients with non-ischemic cardiomyopathy.

3.098. Relative peripheral refraction predicts myopia progression in children

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Vertical and horizontal relative peripheral refraction (RPR) are associated with faster axial length progression and higher risk of incident myopia, according to a study published online June 16 in the American Journal of Ophthalmology.

3.099. Cilia discovered as link between autism and heart defects—offers hope for early autism diagnosis

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Autism spectrum disorders are complex neurodevelopmental conditions affecting about 1 in 100 children worldwide. Early diagnosis would allow timely intervention to improve the development and quality of life for children with autism. Scientists have identified over 200 genes associated with autism, but predicting the risk of developing autism based on genetic information is not straightforward.

3.100. Oncolytic virus immunotherapy shows promise in HR+/HER2- breast cancer trial

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The official results of the BRACELET-01 (PrECOG 0113) trial have been published in Clinical Cancer Research, detailing the safety and efficacy of pelareorep, an investigational oncolytic virus immunotherapy, when added to paclitaxel chemotherapy, both with and without the checkpoint inhibitor avelumab.

3.101. Nearly 30 people in England get rare illness after Botox

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Dozens of people in northeastern England have developed a rare and dangerous illness after receiving Botox injections, according to health officials in the U.K.

3.102. Researchers find that genetic ancestry influences how gene mutations impact cancer prognosis

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Investigators have unveiled for the first time that changes in certain genes affect an aggressive cancer, T-cell acute lymphoblastic leukemia (T-ALL), differently depending on genetic ancestry.

3.103. Novel study uncovers the critical role of ADAM10 protein in the development of retinal disorders

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New research has found that the endothelial cell-specific A disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) regulates abnormal blood vessel growth in the damaged retina, which can cause vision loss or impairment.

3.104. Fusion superkine and focused ultrasound could enable targeted, noninvasive therapy for glioblastoma

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Researchers at VCU Massey Comprehensive Cancer Center and the VCU Institute of Molecular Medicine (VIMM) have discovered a new and potentially revolutionary way to treat glioblastoma (GBM), the most aggressive type of brain cancer, which currently has no curative treatment options.

3.105. Cell therapy improves overall survival of patients with colorectal cancer, study finds

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Colorectal cancer (CRC) is the second most common cause of death from cancer in the US and the most prevalent malignant tumor worldwide. CRC refers to cancer in the colon or rectum, the two parts that make up the large intestine. In the US, deaths from CRC in people under 55 have been increasing since the mid-2000s, highlighting the need for effective treatments.

3.106. Q&A: Researcher discusses how buying primary care on the free market adds to doctor shortages

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Burned-out primary care physicians are increasingly seeking safe haven in concierge care and other free-market models of practice. This has resulted in an exodus from traditional primary care practices and exacerbated an already acute shortage of primary care physicians. These alternative models also give patients more personalized care and attention. But for the rest of people who get their primary care from traditional practices, the already pressing shortage of primary care doctors often gets worse.

3.107. Best practice recommendations for clinical homologous recombination deficiency testing published

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The Association for Molecular Pathology announced the publication of best practice recommendations for clinical laboratories developing and performing homologous recombination deficiency (HRD) testing. The manuscript, titled "Recommendations for Clinical Molecular Laboratories for Detection of Homologous Recombination Deficiency in Cancer: A Joint Consensus Recommendation of the Association of Molecular Pathology, Association of Cancer Care Centers and College of American Pathologists," was published in The Journal of Molecular Diagnostics.

3.108. New study explains why your skin feels tight at the beach: It's the salt water

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Has your skin ever felt tight and dry after coming out of the ocean? You're not just imagining it. Scientists from Binghamton University, State University of New York have confirmed what beachgoers have felt for years—salt water dries out your skin—and why it happens.

3.109. Study finds omega-3 fats may raise some inflammation indicators in the body

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Omega-3 fatty acids, popularly believed to reduce inflammation in the body, appear to increase certain inflammatory markers, researchers have found.

3.110. First-of-its-kind dataset illuminates gene activity in African populations

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The newly launched South African Blood Regulatory (SABR) dataset reveals how genetic variation influences blood traits and gene activity in African populations, providing crucial insights into diseases like diabetes and heart disease.

3.111. Scientists uncover cells' survival strategy in low-nutrient environments

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UCLA scientists have uncovered a surprising survival strategy in cells, especially cancer cells, that may help explain how they adapt and keep growing even when nutrients are scarce and under metabolic stress. Their findings are published in Cancer & Metabolism.

3.112. How new information triggers the brain to navigate changing environments

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In a paper published in the journal Nature Communications, biomedical engineers have shown how two brain regions quickly adapt to shift focus from one planned destination to another.

3.113. Researchers develop first test of cure for Chagas disease

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Researchers at the University of Georgia's Center for Tropical and Emerging Global Diseases have developed the first test to determine whether treatment for Chagas disease was effective. The study is published in the journal eLife.

3.114. International study reveals glyphosate weed killers cause multiple types of cancer

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A comprehensive carcinogenicity study on the world's most used herbicide, glyphosate, involving scientists from Europe and the U.S., has found that low doses of the controversial weed killer cause multiple types of cancer in rats.

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