Childhood gastrointestinal disorders may be predictive for interstitial cystitis

For the 300,000 Americans living with the immune disease scleroderma, better treatments can't come soon enough. The rare and sometimes fatal illness stiffens and scars tissue in organs like the lungs, liver, and kidneys, as well as skin. It may quietly affect one patch of skin for years or rapidly turn life-threatening, depending on where and how severely it strikes.

Molecules exhaled in the breath may help detect blood cancer, according to new research from Queen Mary University of London. The findings could enable the development of a blood cancer breathalyzer, providing a rapid, low-cost way to detect disease. This tool may be particularly useful for areas with limited access to specialist equipment or expertise.

A promising breakthrough in cancer treatment is taking shape at the University of Missouri Research Reactor (MURR), where scientists are developing a powerful radioisotope that could one day precisely target and destroy cancer cells.

A new study led by Georgia State University researchers has found that more than 84% of youth and young adults who use e-cigarettes have modified their device, often in potentially dangerous ways.

Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in protein synthesis and folding.

The World Health Organization warned on Tuesday a major chikungunya virus epidemic risks sweeping around the globe, calling for urgent action to prevent it.

Lymphoid-derived conventional dendritic cells (L-cDCs) may play a unique function associated with immune suppression and allergy induction, as reported by researchers from Japan. Long thought to arise only from myeloid lineages, cDCs were found to also originate from lymphoid progenitors. Using fluorescent reporter mice, the team tracked L-cDCs throughout the body, revealing their abundance in barrier tissues like skin and lungs and their distinct genetic signatures and functions.

A new exploratory analysis of the HIMALAYA phase III trial involving patients with unresectable hepatocellular carcinoma (uHCC, an advanced liver cancer that could not be treated with surgery or other localized treatments) has shown that one in five (19.6%) participants treated with STRIDE (Single Tremelimumab Regular Interval Durvalumab) a combination of two immunotherapies, remained alive after five years of follow-up versus one in 10 (9.4%) participants treated with sorafenib, a standard treatment for uHCC when the study was designed.

Researchers at Oregon Health & Science University have identified a gene that plays a crucial role in the brain's ability to form the protective layer around nerves known as myelin, potentially opening new doors to treatments for a rare childhood disorder and more common diseases such as multiple sclerosis.

A pioneering international survey of people living with eating disorders has found that cannabis and psychedelics, such as "magic mushrooms" or LSD, were best rated as alleviating symptoms by respondents who self-medicated with the non-prescribed drugs.

Antibiotic resistance is one of the biggest health threats we face today. It's often blamed on the overuse of antibiotics, and for a good reason. But there's another major factor quietly driving this crisis that doesn't get as much attention: low vaccination rates.

New research from Karolinska Institutet demonstrates a link between inflammatory bowel disease and faster cognitive decline among dementia patients. The study, which is published in the journal Gut, indicates a need for personalized treatments, researchers say.

Researchers at Keele University have published the first investigation into the variation in the chemical makeup of calcifications caused by prostate cancer, in the hope of identifying new markers to improve early diagnosis.

The late, great comedian Barry Humphries (of Dame Edna fame) once spoke whimsically about the health benefits of kale. Just one fistful, he joked, contained enough essential vitamins, minerals and trace elements to keep you in a sedentary position in the bathroom for two whole days. Apparently, it wasn't tasty enough to justify a second helping.

Living near green spaces before and during pregnancy as well as in early childhood is associated with a reduced risk of neurodevelopmental disorders, according to Rutgers Health researchers.

Nearly half of drug-caused deaths by health care workers involved drugs that were obtained from their place of work, new research finds.

Aging skin stretches, contracts and buckles under pressure—and that's how wrinkles form, according to new experimental evidence from scientists at Binghamton University, State University of New York.

With an estimated 1.5 million new cases and 397,000 deaths worldwide, prostate cancer is the world's second most frequent cancer and the fifth leading cause of cancer death among men in 2022. Hormone therapy based on the inhibition of androgen receptor signaling (ARPi) is the mainstay of treatment for metastatic prostate cancer (mPC). However, cancer drug resistance ultimately arises, highlighting the need for more effective therapeutic strategies.