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Cholera outbreaks worsening, spreading to 31 countries: WHO

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  • 2025-08-30 00:25 event
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Cholera outbreaks worsening, spreading to 31 countries: WHO
The global cholera situation is worsening, with outbreaks across 31 countries and a surging fatality rate, the World Health Organization said Friday.

1.316. Leukemia stem cell-based method aids relapse prediction in acute myeloid leukemia

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An assay that uses leukemia stem cells (LSCs) to assess measurable residual disease (MRD) outperforms traditional methods in patients with acute myeloid leukemia (AML), according to a study published online Aug. 23 in Bone Marrow Transplantation.

1.317. Clinical trial shows constipation drug can treat patients with chronic kidney disease

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Chronic kidney disease (CKD) is a major health issue worldwide. Many patients end up requiring regular dialysis to avoid kidney failure and stay alive. Despite the severity of the condition, there are currently no drugs available that improve kidney function.

1.318. Geriatric assessment in the emergency department reduces admission rates

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A comprehensive assessment of older adults being seen in the emergency department can help reduce hospital admissions, according to a study published online Aug. 21 in the Annals of Emergency Medicine.

1.319. Unlocking the immune system: Cellular 'toolkit' could reprogram cells for cancer therapy

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An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialized immune cells. The discovery, published in Immunity, could pave the way for more precise and personalized cancer immunotherapies.

1.320. 2010 to 2023 saw decline in births, increase in deaths in the United States

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From 2010 to 2023, the number of births in the United States declined, and the number of deaths increased, according to the Aug. 27 National Vital Statistics Reports, a publication from the National Center for Health Statistics.

1.321. How the distinctive folds in the brain cortex, seen in humans, whales, other animals, form

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One of the defining features of humans is our brain's remarkable capacity for language, planning, memory, creativity, and more. These abilities stem not just from our large brain size, but also from the folded structure of the brain's outer layer, the cerebral cortex.

1.322. Organoid-based platform enables precise evaluation of antibody and vaccine efficacy

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A research team has successfully developed the world's first nasal organoid-based SARS-CoV-2 neutralizing antibody evaluation platform.

1.323. With CDC in chaos, scientists and physicians piece together replacements for agency's lost work

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The CDC is in chaos and some groups are starting to step in and take over work the agency was doing.

1.324. Death toll from Legionnaires' disease outbreak in New York City rises to 7 and infections hit 114

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New York City health officials have discovered a seventh death linked to a Legionnaires' disease outbreak in Central Harlem, where more than 100 people have been diagnosed with the ailment.

1.325. Cholera outbreaks worsening, spreading to 31 countries: WHO

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The global cholera situation is worsening, with outbreaks across 31 countries and a surging fatality rate, the World Health Organization said Friday.

1.326. Metals and sulfate in air pollution mixture may contribute most to asthma hospitalizations

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Metals, particularly nickel and vanadium, and sulfate particles are the components of fine particulate air pollution (PM2.5) that most strongly contribute to the association between long-term exposure to air pollution and hospitalization among asthma sufferers, according to a new study led by Harvard T.H. Chan School of Public Health.

1.327. DNA variants that increase testosterone production in PCOS patients identified

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Increased testosterone levels are a consistent hormonal abnormality in women with polycystic ovary syndrome (PCOS). A study has identified specific DNA variants in the gene DENND1A, which increase testosterone production in PCOS. Using human PCOS cell models, researchers demonstrated that activating these DNA switches turns on DENND1A and drives testosterone production. This provides the first direct evidence that inherited DNA changes can cause the hormone imbalance at the core of PCOS.

1.328. Researchers determine how cells prevent RNA traffic jams under stress

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A University of Michigan study offers fresh insights into how cells manage molecular crises.

1.329. Retinitis pigmentosa mouse models reflect pathobiology of human RP59

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Retinitis pigmentosa retinal degeneration is caused by a family of hereditary mutations in nearly 100 genes that slowly lead to blindness over years or decades.

1.330. Active ingredient from red foxglove helps with heart failure, clinical study confirms

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Digitalis has been used to treat heart failure for more than 200 years. The drug digitoxin also belongs to this group of active ingredients known as cardiac glycosides.

1.331. Common inflammation drug may slow blood mutation, related cardiovascular disease risk

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Taking low-dose colchicine daily may slow the progression of a common acquired gene mutation found in the blood of older adults that can lead to certain blood cancers and increased risk of cardiovascular disease (CVD), according to a subanalysis of the LoDoCo2 trial published in JACC, the flagship journal of the American College of Cardiology, and simultaneously presented at ESC Congress 2025.

1.332. Large-scale study reveals 'flat-line ECG' indicates poor outcomes for out-of-hospital cardiac arrest

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Asystole is the most serious form of cardiac arrest. It happens when the heart stops beating and there is no more electrical activity. It is sometimes called "flat-line" or "flat-lining" because the lines on an electrocardiogram become flat when electrical activity ceases.

1.333. Home-based heart rhythm screening improves diagnosis of common heart condition

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A wearable electrocardiogram (ECG) patch increases diagnosis of a common heart rhythm disorder, according to a study led by researchers at Oxford Population Health. The results of the Active Monitoring for Atrial Fibrillation (AMALFI) trial have been published in the American Heart Journal and were presented at the European Society of Cardiology Congress 2025.

1.334. Stem cell research takes a step toward smart blood sugar control in diabetes

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Professor Deng Hongkui's team from the Peking University School of Life Sciences has made the first successful differentiation of human pluripotent stem cells into fully endocrine-subtype-complete islets. These islets efficiently respond to blood glucose concentration changes, demonstrating very effective blood sugar control capabilities.

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