Clinical trial tests speech therapy for rare neurological disorder

Cleveland Clinic Cole Eye Institute researchers have identified a potential association between the use of GLP-1 receptor agonist (GLP-1RA) therapy and a reduced risk of non-infectious uveitis, a type of eye inflammation.

Moderate exercise in older age shapes brain activity which can reduce the number of "tip of the tongue" moments, as new research shows that higher cardiorespiratory fitness alters our brain's ability to reach for the right word at the right time.

Waking up with a pimple is no longer a cause for panic, thanks to pimple patches—small, sticker-like bandages that cover and help heal the unwanted zit. A team of researchers publishing in ACS Applied Materials & Interfaces has designed a two-stage pimple patch set with an array of tiny spikes that grabs onto the pimple and delivers antibacterial or anti-inflammatory compounds. Human clinical trials confirmed that the pimples completely disappeared after seven days of treatment.

A UdeM study upends the hypothesis that experienced dancers don't get dizzy from doing pirouettes because they can suppress their vestibular system.

All cells naturally produce formaldehyde as a byproduct of metabolism. To survive this toxic stress, both healthy and cancerous blood-forming cells rely on a built-in defense system. Now, scientists at the Lewis Katz School of Medicine at Temple University have discovered that leukemia cells generate far greater amounts of formaldehyde than normal blood cells and that to survive this stress, they rely on a unique protective mechanism.

Every year, global health experts are faced with a high-stakes decision: Which influenza strains should go into the next seasonal vaccine? The choice must be made months in advance, long before flu season even begins, and it can often feel like a race against the clock. If the selected strains match those that circulate, the vaccine will likely be highly effective. But if the prediction is off, protection can drop significantly, leading to (potentially preventable) illness and strain on health care systems.

Northwestern Medicine scientists have discovered how a common virus linked to birth defects and chronic illness manipulates its host's DNA, according to a new study published in Nature Communications.

Some regions of the brain in people with Alzheimer's reorganize more often while at rest than in people without the disease––and in healthy people this frequent reshuffling sometimes predicts who will develop the condition later, according to a new study from the University of Michigan and Columbia University.

By 2040, experts estimate that nearly 400,000 people worldwide will be living with amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig's disease. This degenerative nervous system disease damages nerve cells responsible for controlling voluntary muscle movement, leading to progressive muscle weakness, loss of muscle mass and, eventually, difficulty breathing. Current ALS diagnosis relies on neurological evaluations and the presence of symptoms; at present, there is no definitive diagnostic test.

A University of Alberta-led team has identified a new way to treat post-surgical pain in animals and human cells, in a bid to find non-addictive treatments for acute and even chronic pain.

Many modern cancer treatments are highly effective at reducing or eliminating tumors, but they can also cause severe gastrointestinal symptoms that impact patients' quality of life or lead to discontinuation of treatment. A new analysis from University of Illinois Urbana-Champaign researchers reveals the nutrition therapies that are most effective at minimizing GI distress. The research is published in the journal Advances in Nutrition.

People with leukemia have a weakened immune system due to the disease itself and treatment, which leads to an increased susceptibility to infections. In a revised guideline, experts summarize the findings of the past ten years on all viruses that cause respiratory infections: How dangerous are they in detail? How are they diagnosed? Are hygiene measures necessary? What treatment and vaccination strategies are available?

Fewer than half of people diagnosed with a subtype of myeloid/lymphoid neoplasms are alive one year later. A multicenter Phase II trial, called FIGHT-203, led by Stanford Medicine, has led to FDA approval of a new drug treatment.

Testing the molecular profile of tumors identifies which patients with advanced prostate cancer are more likely to benefit from chemotherapy and live longer, sparing patients less likely to benefit from unpleasant side effects, according to a new study led by UCL researchers.

New proteomics research is enabling scientists to decipher how neurotransmitter receptors behave and change as an organism develops. The new work could help scientists better understand the formation and function of synapses—the junctions where communication signals are passed between neurons.

People with rheumatoid arthritis (RA) often have trouble getting out of bed in the morning, let alone getting to the rheumatologist for a checkup or participating in a research study. This makes a deeper understanding of the mysterious autoimmune disease all the more difficult. That's a significant problem, because RA affects more than 1.5 million people in the U.S. and 18 million people worldwide—and as of now, there's no cure.

A new global systematic literature review and meta-analysis has shown that herpes zoster vaccination, used to prevent shingles, is associated with a statistically significant lower risk of heart attack and stroke.

My travels with autism started long before my diagnosis, at the age of three years and three months.