Injectable obesity medications associated with reduced risk for eye inflammation

Children with acute lymphoblastic leukemia (ALL) from the lowest socioeconomic status (SES) neighborhoods have an increased risk for mortality, according to a study published online Aug. 22 in Blood Advances.

In 2023, more than 2.4 million cases of syphilis, gonorrhea, and chlamydia were diagnosed in the U.S. Though that number is high, it's actually an improvement, according to the Centers for Disease Control and Prevention: The number of sexually transmitted infections, or STIs, decreased 1.8% overall from 2022 to 2023, with gonorrhea decreasing the most (7.2%).

New research from cardiovascular scientists at UC Davis Health reveals that stress affects more than just the mind—it also alters heart function at the molecular level.

Long-term cocoa extract supplementation does not reduce the risk for incident hypertension but does reduce hypertension incidence among those with normal systolic blood pressure (BP) at baseline, according to a study published online Aug. 20 in Hypertension.

The sexually transmitted disease gonorrhea has increased in the past 10 years. No one knows exactly why gonorrhea is spreading—but experts suspect a mix of better testing and changing sexual habits. At the same time, we face reduced treatment options due to antimicrobial resistance.

A research team led by the Department of Medicine and the Department of Orthopedics and Traumatology, under the School of Clinical Medicine, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), has uncovered a serious risk of joint infection following knee surgery, linked to allergy mislabeling.

An artificial intelligence (AI)-enabled bundled system of sensors and coaching facilitates significant improvements in glycemic outcomes and de-escalation of glucose-lowering pharmacotherapy, according to a study published online Aug. 20 in NEJM Catalyst.

A new research letter published Aug. 25 in JAMA Pediatrics estimates the extent to which obesity-related conditions (ORCs) are tied to obesity and overweight in adolescents and young adults in the United States. In this paper, lead author and medical student, Ashwin Chetty used publicly available data from the National Health and Nutrition Examination Survey (NHANES) to quantify how much obesity can cause obesity-related conditions and what the impact of preventing or treating obesity could be.

A world-first clinical trial has found that a simple daily nasal spray can significantly reduce the risk of COVID-19 in cancer patients, offering a potential new tool to protect vulnerable people from the virus.

Moderate exercise in older age shapes brain activity which can reduce the number of "tip of the tongue" moments, as new research shows that higher cardiorespiratory fitness alters our brain's ability to reach for the right word at the right time.

Waking up with a pimple is no longer a cause for panic, thanks to pimple patches—small, sticker-like bandages that cover and help heal the unwanted zit. A team of researchers publishing in ACS Applied Materials & Interfaces has designed a two-stage pimple patch set with an array of tiny spikes that grabs onto the pimple and delivers antibacterial or anti-inflammatory compounds. Human clinical trials confirmed that the pimples completely disappeared after seven days of treatment.

A UdeM study upends the hypothesis that experienced dancers don't get dizzy from doing pirouettes because they can suppress their vestibular system.

All cells naturally produce formaldehyde as a byproduct of metabolism. To survive this toxic stress, both healthy and cancerous blood-forming cells rely on a built-in defense system. Now, scientists at the Lewis Katz School of Medicine at Temple University have discovered that leukemia cells generate far greater amounts of formaldehyde than normal blood cells and that to survive this stress, they rely on a unique protective mechanism.

Every year, global health experts are faced with a high-stakes decision: Which influenza strains should go into the next seasonal vaccine? The choice must be made months in advance, long before flu season even begins, and it can often feel like a race against the clock. If the selected strains match those that circulate, the vaccine will likely be highly effective. But if the prediction is off, protection can drop significantly, leading to (potentially preventable) illness and strain on health care systems.

Northwestern Medicine scientists have discovered how a common virus linked to birth defects and chronic illness manipulates its host's DNA, according to a new study published in Nature Communications.

Some regions of the brain in people with Alzheimer's reorganize more often while at rest than in people without the disease––and in healthy people this frequent reshuffling sometimes predicts who will develop the condition later, according to a new study from the University of Michigan and Columbia University.

By 2040, experts estimate that nearly 400,000 people worldwide will be living with amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig's disease. This degenerative nervous system disease damages nerve cells responsible for controlling voluntary muscle movement, leading to progressive muscle weakness, loss of muscle mass and, eventually, difficulty breathing. Current ALS diagnosis relies on neurological evaluations and the presence of symptoms; at present, there is no definitive diagnostic test.

Researchers have led the largest clinical study to date investigating speech therapy for people with a rare, rapidly progressive and fatal neurological condition.