Liver fat, not weight, predicts health risks in obese children

Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally leak out in the process, causing damage to the cell. However, researchers at the University of Freiburg's Cluster of Excellence CIBSS—Center for Integrative Biological Signaling Studies succeeded in demonstrating that a protective mechanism takes effect at this moment.

Military conflict has led to heightened risk of cognitive problems in performing day-to-day activities among some war zone veterans, which can result in increased burden on family members.

US president Donald Trump's claim that pregnant women should avoid acetaminophen—a statement that is both harmful and not backed by the science—fits into a long and damaging tradition of blaming parents, especially mothers, for autism.

You may want to think twice before snacking on a Slim Jim or downing a soda. They could alter your brain health over time.

Emergency departments may be missing opportunities to identify and treat people for problem alcohol use. A new study published in Alcohol, Clinical and Experimental Research found that less than 1% of emergency department patients who screened positive for high-risk drinking received a prescription for a medication to treat the disorder. More than half of those who did receive a prescription filled it, suggesting that increasing awareness and education among emergency department clinicians may be an effective avenue for improving treatment for people with high-risk drinking.

Among people in treatment for alcohol dependence, the severity of withdrawal symptoms during early alcohol abstinence may be affected by the life adversity they have experienced, a small study suggests. "Cumulative adversity" is the sum of an individual's challenging and traumatic life circumstances. This chronic wear and tear is associated with a range of health outcomes—including substance use disorders, where the effects of stress are known to underpin craving and relapse.

The tiny fruit fly could have a mighty impact on identifying optimal treatments for people with alcohol use disorder. A new study confirmed that using fruit flies may help scientists understand the human body's response to certain medications that influence alcohol use patterns.

Changing cannabis use frequency may predict changes in binge drinking frequency among young adults, according to a new study that illuminates shifts in substance use across early adulthood. The findings imply opportunities for targeted interventions to prevent and treat binge drinking, a behavior linked to a range of negative consequences, including alcohol use disorder (AUD) and high economic costs.

The most common type of liver cancer in children, hepatoblastoma, surprisingly appears to contain many immune cells from a type that has long been overlooked. This is according to a study by researchers at the Princess Máxima Center and UMC Utrecht. The discovery of these myeloid cells in liver tumors unveils new avenues for treatment.

A new international study led by Mayo Clinic researchers has identified a genetic factor that may explain why some patients with colorectal cancer that has spread to the liver experience more severe liver damage after chemotherapy.

More than 1 million people a year are now being referred by general practitioners (GPs) to social prescribing services, according to a new study led by researchers at UCL.

Northwestern Medicine scientists have developed a comprehensive atlas of genetic coding sequences in both healthy adult hearts and those with heart failure, a resource that has the potential to improve the understanding of heart health and inform the development of new therapeutic targets for cardiovascular disease, as detailed in a recent study published in Circulation.

A new study from the Department of Psychology at Durham University has found that identity distress (difficulty forming a cohesive identity) could be behind the higher rates of poor mental health experienced by autistic people.

Does walking influence how people process sensory information, like sounds, from the environment? In a new JNeurosci paper, researchers led by Liyu Cao, from Zhejiang University, and Barbara Händel, from University of Würzburg, explored whether walking direction influences how people process sounds.

As we mark the first anniversary of flooding from Hurricane Helene that devastated parts of North Carolina, the anesthesia department at the Medical University of South Carolina is sharing how it responded to one effect of that flooding: the disruption of the IV fluid supply chain.

In the dry, isolated area of Karamoja in northeastern Uganda—the country's poorest sub-region—children have long suffered from malnutrition and water shortages.

Lung cancer remains one of the deadliest cancers worldwide, with survival rates stubbornly low despite advances in surgery, chemotherapy, and immunotherapy. But a new discovery may change the way doctors approach treatment.

Depression and anxiety disorders are among the most widespread mental health disorders, with estimates suggesting that they affect around 264 million and 284 million people worldwide, respectively. Depression is a mood disorder characterized by persistent sadness and a loss of interest in everyday activities, while anxiety disorders are marked by high levels of nervousness, worry and fear, either in specific situations or generalized.