New GLP-1 pill helps people lose 23 pounds in study
- medicalxpress.com language
- 2025-08-27 23:50 event
- 3 weeks ago schedule

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A new study of young adults has strongly linked better sleep quality with better mental well-being, with fruit and vegetable consumption and physical activity also strongly associated with psychological well-being. Perhaps surprisingly, the findings also suggest that boosting fruit and vegetable intake could potentially help mitigate the effects on well-being after a poor night's sleep.
An international research team led by UCL, Great Ormond Street Hospital, and KU Leuven is using 3D-printing and nanodiamonds to design treatments that could help babies repair their damaged lungs while still in the womb. The new research is published in the American Journal of Respiratory and Critical Care Medicine.
Certain brain cells are responsible for coordinating smooth, controlled movements of the body. But when those cells are constantly overactivated for weeks on end, they degenerate and ultimately die. This new observation made by scientists at Gladstone Institutes may help explain what goes awry in the brains of people with Parkinson's disease.
Inside every human brain lies a detailed map of the body, with different regions dedicated to different body parts—the hands, lips, feet and more. But what happens to this map when a body part is removed?
Researchers at Karolinska Institutet have discovered that mantle cell lymphoma (MCL), a rare and aggressive type of blood cancer, is already highly diverse at the time of diagnosis and continues to evolve in unique ways in each patient. The work is published in the journal Cell Reports Medicine.
A procedure which uses living heart valves may have expanded application as a treatment for various types of pediatric heart valve conditions.
Could a natural check on cancer be used to stop the disease? It's possible, but to leverage a system that nature designed, we must first understand it. Researchers led by a team at Purdue University are exploring a molecular mechanism that curbs the breakneck cell division associated with cancer. Their work opens the door to developing drugs that capitalize on the mechanism's effects.
A new biochemical approach to combat addiction, developed by researchers at the University of California San Diego and the National Institute on Drug Abuse (NIDA), has shown promising results in reducing drug-seeking behavior.
A study looking at the biophysical properties of an abnormal protein driving cancer cells is giving scientists new therapeutic clues for how to treat ependymoma, the third most common childhood brain tumor.
Eli Lilly says its new once-daily pill, orforglipron, helped people lose significant weight and lower blood sugar in a late-stage clinical trial.
This highlights an important preclinical model that could be successful in humans. The notoriously persistent, difficult-to-treat, lifelong and contagious virus—which insidiously attacks the liver—infects millions, particularly those with compromised immune systems and children. Globally, more than 296 million people are infected, with many living in South Africa.
One third of severely injured trauma patients in the United States are first treated at hospitals designated as Level III or non-trauma centers, and less than half of those patients get transferred out to a Level I trauma center where they can receive more comprehensive trauma care, according to a study published in the Journal of the American College of Surgeons.
"If you can't handle this, you'll never keep up with your peers."
Only a few decades ago, a diagnosis of lupus could mean giving up the dream of having children. Women with systemic autoimmune diseases like lupus were warned that pregnancy was too risky—both for them and their unborn babies. Fast forward to today, and the story is remarkably different.
Texas passed a landmark law in June 2025, supported by former Gov. Rick Perry, that allocates US$50 million to support research on ibogaine, one of the most powerful psychedelics, for treating opioid addiction and treatment-resistant PTSD.
In a new study, artificial intelligence matched and potentially exceeded the performance of gastroenterologists and conventional scoring in evaluating endoscopies of Crohn's disease patients.
Researchers at the University of California San Diego School of Medicine have identified a new investigational drug that shows promise in treating metabolic dysfunction-associated steatohepatitis (MASH), a serious form of fatty liver disease linked to obesity and type 2 diabetes that can lead to cirrhosis, liver failure, and even liver cancer.
In my youth, I spent an unreasonable amount of time questioning why A-level chemistry was a prerequisite for medical school. Why was it as essential as biology? Why did I need to learn about electrons and entropy? The penny finally dropped when my rather brilliant teachers turned my attention towards the periodic table.
A novel, multi-analyte test developed by researchers at the Johns Hopkins Kimmel Cancer Center, its Ludwig Center and the Johns Hopkins Department of Neurosurgery can accurately identify brain cancers using small samples of cerebrospinal fluid (CSF), offering a promising new tool to guide clinical decision-making.