Test detects brain cancers in cerebrospinal fluid with high accuracy

Eli Lilly says its new once-daily pill, orforglipron, helped people lose significant weight and lower blood sugar in a late-stage clinical trial.

This highlights an important preclinical model that could be successful in humans. The notoriously persistent, difficult-to-treat, lifelong and contagious virus—which insidiously attacks the liver—infects millions, particularly those with compromised immune systems and children. Globally, more than 296 million people are infected, with many living in South Africa.

One third of severely injured trauma patients in the United States are first treated at hospitals designated as Level III or non-trauma centers, and less than half of those patients get transferred out to a Level I trauma center where they can receive more comprehensive trauma care, according to a study published in the Journal of the American College of Surgeons.

"If you can't handle this, you'll never keep up with your peers."

Only a few decades ago, a diagnosis of lupus could mean giving up the dream of having children. Women with systemic autoimmune diseases like lupus were warned that pregnancy was too risky—both for them and their unborn babies. Fast forward to today, and the story is remarkably different.

Texas passed a landmark law in June 2025, supported by former Gov. Rick Perry, that allocates US$50 million to support research on ibogaine, one of the most powerful psychedelics, for treating opioid addiction and treatment-resistant PTSD.

In a new study, artificial intelligence matched and potentially exceeded the performance of gastroenterologists and conventional scoring in evaluating endoscopies of Crohn's disease patients.

Researchers at the University of California San Diego School of Medicine have identified a new investigational drug that shows promise in treating metabolic dysfunction-associated steatohepatitis (MASH), a serious form of fatty liver disease linked to obesity and type 2 diabetes that can lead to cirrhosis, liver failure, and even liver cancer.

In my youth, I spent an unreasonable amount of time questioning why A-level chemistry was a prerequisite for medical school. Why was it as essential as biology? Why did I need to learn about electrons and entropy? The penny finally dropped when my rather brilliant teachers turned my attention towards the periodic table.

A UCLA study has mapped a critical brain hub in mice that regulates stress responses and social behavior, shedding new light on the neural roots of psychiatric conditions such as post-traumatic stress disorder, depression and anxiety.

Investigators at Mass General Brigham and the Richard A. and Susan F. Smith Center for Outcomes Research at Beth Israel Deaconess Medical Center have uncovered how patients' health care spending has changed following the implementation of the No Surprises Act in 2022, a bipartisan law prohibiting unexpected or "surprise" bills after patients receive out-of-network medical care.

Government housing assistance was associated with a nearly seven-percentage point lower risk of experiencing financial hardship related to medical expenses among US renters with a history of cancer, new research finds.

Scientists at Kumamoto University have made a major breakthrough in regenerative medicine by successfully creating functional ureter tissue—organoids resembling the urinary tract—from pluripotent stem cells. The results, published in Nature Communications, bring researchers one step closer to developing transplantable kidneys capable of producing and expelling urine.

A new editorial published in JMIR Medical Informatics examines the rapid rise of ambient artificial intelligence (AI) scribes—technologies designed to automate clinical documentation and ease the administrative burden on health care practitioners. While these tools show great promise in reducing burnout and freeing up time for patient care, the editorial highlights significant concerns that warrant further investigation.

The U.S. Centers for Disease Control and Prevention (CDC) will stop airing its "Tips From Former Smokers" ads at the end of September, ending a 13-year campaign that helped millions of Americans quit smoking.

By stimulating macrophages—a type of white blood cell—with biological factors that mimic infection, researchers have uncovered genetic drivers of complex diseases such as inflammatory bowel disease (IBD), in one of the largest studies of its kind.

Treatment with exagamglogene autotemcel (exa-cel) led to robust and sustained improvements in quality of life for patients with severe sickle cell disease (SCD) or transfusion-dependent beta thalassemia, according to two studies published in Blood Advances.

Across the United States, the return of students to college campuses during the COVID-19 pandemic in the fall of 2020 sparked widespread fears that local communities would be overwhelmed by the virus.