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Scientists advance efforts to create 'virtual cell lab' as testing ground for future research with live cells

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  • 2025-07-25 22:00 event
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Scientists advance efforts to create 'virtual cell lab' as testing ground for future research with live cells
Using mathematical analysis of patterns of human and animal cell behavior, scientists say they have developed a computer program that mimics the behavior of such cells in any part of the body. Led by investigators at Indiana University, Johns Hopkins Medicine, the University of Maryland School of Medicine and Oregon Health & Science University, the new work was designed to advance ways of testing and predicting biological processes, drug responses and other cell dynamics before undertaking more costly experiments with live cells.

1.198. Ritz update: FDA issues risk warning due to undeclared peanuts in some cracker sandwiches

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Ritz peanut butter cracker sandwiches are being recalled due to the possible presence of undeclared peanuts, a major allergen.

1.199. Keurig K-Cups recalled due to potential ink contamination

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Keurig K-Cups are being recalled nationwide due to a packaging issue that could cause ink to run into the coffee during brewing.

1.200. Kinshasa slum battles deadly cholera outbreak

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Faced with a lack of running water, unsanitary conditions and poverty, the Kinshasa neighborhood of Pakadjuma has struggled to end a cholera epidemic that has claimed hundreds of lives in the Democratic Republic of Congo (DRC) this year.

1.201. Southern China hit by outbreak of mosquito-borne infection chikungunya

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China is experiencing an outbreak of chikungunya, a mosquito-borne infection, with thousands of cases reported in the south.

1.202. Chromatin organization linked to p53 tumor suppression mechanism

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Each cell in our bodies carries about two meters of DNA in its nucleus, packed into a tiny volume of just a few hundred cubic micrometers—about a millionth of a milliliter. The cell manages this by winding the strings of DNA around protein spools. The protein-DNA complexes are called nucleosomes, and they ensure that DNA is safely stored.

1.203. Study finds roots of mental and neurodegenerative disorders in fetal brain cells

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The origin of some neuropsychiatric diseases, such as autism, bipolar disorder, or depression, and certain neurodegenerative diseases, Alzheimer's and Parkinson's, can be found in very early stages of brain formation in the fetus. That is, earlier than previously recognized, according to a study by the Hospital del Mar Research Institute and Yale University, published in Nature Communications.

1.204. Laminin-411 peptide shows promise for central nervous system myelin repair

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The laminin-411 protein is vital for the formation of the myelin membrane by oligodendrocytes, report researchers from Japan. Furthermore, the A4G47 peptide from the E8 region of laminin-411 was found to be the main active amino acid sequence that drives myelin formation. The research findings have the potential to transform current cell culture practices to study myelination and may enable the development of novel therapeutic agents to treat demyelinating diseases.

1.205. Newly discovered cellular trigger could lead to possible therapies for Parkinson's disease

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Autophagy is essentially the "rubbish collection" of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest study, leading cell biologists at the Max Perutz Labs at the University of Vienna investigated mitophagy—a form of autophagy—and came to a remarkable conclusion: the researchers have described a new trigger for mitophagy.

1.206. Surrogates more likely to be diagnosed with mental illness, study finds

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People who are gestational carriers (or "surrogates") appear more likely to be diagnosed with a new mental illness during and after pregnancy, according to new research from ICES, McGill University, and the Research Institute of the McGill University Health Center.

1.207. Scientists advance efforts to create 'virtual cell lab' as testing ground for future research with live cells

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Using mathematical analysis of patterns of human and animal cell behavior, scientists say they have developed a computer program that mimics the behavior of such cells in any part of the body. Led by investigators at Indiana University, Johns Hopkins Medicine, the University of Maryland School of Medicine and Oregon Health & Science University, the new work was designed to advance ways of testing and predicting biological processes, drug responses and other cell dynamics before undertaking more costly experiments with live cells.

1.208. Globally, over 2.5 million COVID deaths prevented worldwide thanks to vaccines, data indicate

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Thanks to vaccinations against SARS-CoV-2 in the period 2020–2024, 2.533 million deaths were prevented at the global level; one death was avoided for every 5,400 doses of vaccine administered.

1.209. Scientists develop tissue-healing gel using milk-derived extracellular vesicles

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Researchers from Columbia Engineering have established a framework for the design of bioactive injectable hydrogels formulated with extracellular vesicles (EVs) for tissue engineering and regenerative medicine applications.

1.210. First-of-its kind study reveals psychological toll of war in Gaza extends far beyond the region

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The ongoing conflict in the Middle East is having a significant impact on the mental health and well-being of Australian women who migrated from directly impacted countries, or have family ties to the region, according to researchers from UNSW Sydney and The Australian National University (ANU).

1.211. Elite soccer players master the art of trapping without breaking their stride: Study

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In soccer games, "ball-trapping"—quickly changing direction after receiving a pass to transition into an attack—is a critical maneuver. This action can significantly influence the flow of a match, especially when executed effectively in the space between an opponent's midfield and defensive lines. However, the specific physical techniques used by skilled ball-trappers during actual gameplay have not been well understood.

1.212. Number of family caregivers has skyrocketed in the US

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The number of Americans caring for an older or disabled family member has risen dramatically during the past 10 years, according to a new AARP policy report.

1.213. Plant virus triggers immune response that targets and destroys cancer cells

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A virus that typically infects black-eyed peas is showing great promise as a low-cost, potent cancer immunotherapy—and researchers are uncovering why.

1.214. New research uncovers gene impacts of PFAS exposure in firefighters

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Researchers at the University of Arizona Mel and Enid Zuckerman College of Public Health found that certain kinds of long-lasting chemicals firefighters are exposed to may affect the activity of genes linked to cancer and other diseases. The findings appear in the journal Environmental Research.

1.215. What is chikungunya virus, and should we be worried about it in Australia?

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This week, the World Health Organization (WHO) raised concerns about a surge in the number of cases of a mosquito-borne viral infection called chikungunya.

1.216. Gene therapy trial offers breakthrough for rare genetic disorder

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A study evaluating a pioneering lentivirus (LV)-mediated gene therapy trial for classical Fabry disease showed promising results over five years, indicating a potential breakthrough in treatment for the genetic disorder.

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