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Around 10 million people globally live with the life-threatening virus HTLV-1. Yet it remains a poorly understood disease that currently has no preventative treatments and no cure.
Cellular senescence is a process in which the cell cycle becomes permanently arrested, thereby inhibiting cell division, proliferation and growth. Various cellular stresses, such as DNA damage, telomere shortening and oxidative stress, can trigger cellular senescence. Physiologically, cellular senescence contributes to tissue development, repair and critical biological processes such as embryogenesis, whereas, pathologically, it plays a key role in diverse conditions, including age-related disease, some cancers, Alzheimer's disease, and others.
A study by investigators at the Icahn School of Medicine at Mount Sinai, in collaboration with colleagues from Rabin Medical Center in Israel and other collaborators, suggests that even the most advanced artificial intelligence (AI) models can make surprisingly simple mistakes when faced with complex medical ethics scenarios.
An antibody treatment developed at Stanford Medicine successfully prepared patients for stem cell transplants without toxic busulfan chemotherapy or radiation, a Phase I clinical trial has shown.
Jerusalem, Cairo, Geneva, 22 July 2025 WHO condemns in the strongest terms the attacks on a building housing WHO staff in Deir al Balah, in the middle area of Gaza, the mistreatment of those sheltering there, and the destruction of its main warehouse. Following intensified hostilities in Deir al Balah after the latest evacuation order issued by Israeli military, the WHO staff residence was attacked three times today. Staff and their families, including children, were exposed to grave danger and traumatized after airstrikes caused a fire and significant damage. Israeli military entered the premises, forcing women and children to evacuate on foot toward Al-Mawasi amid active conflict. Male staff and family members were handcuffed, stripped, interrogated on the spot, and screened at gunpoint. Two WHO staff and two family members were detained. Three were later released, while one staff member remains in detention. Thirty-two people, including women and children, were collected and evacuated to the WHO office in a high-risk mission, once access became possible. The office itself is close to the evacuation zone and active conflict. WHO demands continuous protection of its staff and the immediate release of the remaining detained staff member. The latest evacuation order has affected several WHO premises. As the United Nations’s (UN) lead health agency, WHO’s operational presence in Gaza is now compromised, crippling efforts to sustain a collapsing health system and pushing survival further out of reach for more than two million people. Most of WHO’s staff housing is now inaccessible. Last night, due to intensified Read more...
Patients prescribed drugs to help them lose weight may experience a rebound in weight gain after halting their prescription, finds a meta-analysis published in BMC Medicine.
Heart failure patients living in the most deprived postcodes are at risk of dying six and a half months earlier than patients in the least deprived areas, according to a new study published in the journal BMC Medicine. The research also found that the disparities in risk of death and life expectancy worsened over time.
Poisonings and deaths linked to the use of the local anesthetic lidocaine have nearly tripled in the US over the past decade, finds an analysis of National Poison Data System (NPDS) reports, published online in the journal Regional Anesthesia & Pain Medicine.
A new study by McMaster University researchers has found that many people with irritable bowel syndrome (IBS) who believe they are sensitive to gluten or wheat may not actually react to these ingredients.
Exposure to a class of synthetic chemicals known as per- and polyfluoroalkyl substances (PFAS)—often called "forever chemicals"—may increase the risk of developing type 2 diabetes, according to a new study led by Mount Sinai researchers. The findings were published in eBioMedicine.
For patients with idiopathic intracranial hypertension (IIH), glucagon-like peptide 1 receptor agonist (GLP-1 RA) treatment is associated with improved clinical outcomes compared with conventional therapies, according to a study published online July 14 in JAMA Neurology.
For adults with neurogenic lower urinary tract dysfunction (NLUTD) or interstitial cystitis/bladder pain syndrome (IC/BPS), robot-assisted laparoscopic supratrigonal cystectomy with augmentation cystoplasty (RA-SC-AC) is feasible, according to a study published in the July issue of BJUI Compass.
A prospective cohort study examined the associations of different physical activity patterns with all-cause, cardiovascular (CV) and cancer mortality among adults with diabetes.
Matthew Leming, Ph.D., and Hyungsoon Im, Ph.D. of the Center for Systems Biology at Massachusetts General Hospital, are the co-corresponding authors of a paper published in Alzheimer's & Dementia, "Differential dementia detection from multimodal brain images in a real-world dataset."
Close to 5 million above-ground swimming pools have been recalled following the drowning deaths of nine children over two decades.
A team led by José Antonio Gil Gómez (Universitat Politècnica de València) and Inmaculada Montoya Castilla (Universitat de València) has developed emoWELL, a video game that helps improve emotional management in young people between the ages of 18 and 25.
In a study published in Alzheimer's & Dementia, a team led by Dr. Sha Feng from the Shenzhen Institute of Advanced Technology of the Chinese Academy of Sciences—collaborating with Dr. Jed A. Barash from the Massachusetts Veterans Home at Chelsea and Prof. W. Andrew Kofke from the University of Pennsylvania—has found that regular opioid use is associated with an increased risk of dementia, particularly vascular dementia.
Many people with cancer experience dramatic loss of muscle and fat tissue. In many cases, even the heart muscle is affected, which further weakens the body. This wasting syndrome, known as cachexia, affects around half of all cancer patients. It is a major cause of therapy resistance, complications, and increased mortality.
Found in everything from protein bars to energy drinks, erythritol has long been considered a safe alternative to sugar. But new research suggests this widely-used sweetener may be quietly undermining one of the body's most crucial protective barriers—with potentially serious consequences for heart health and stroke risk.