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Why women's brains face higher risk: Scientists pinpoint X-chromosome gene behind MS and Alzheimer's

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  • 2025-10-16 01:00 event
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Why women's brains face higher risk: Scientists pinpoint X-chromosome gene behind MS and Alzheimer's
New research by UCLA Health has identified a sex-chromosome linked gene that drives inflammation in the female brain, offering insight into why women are disproportionately affected by conditions such as Alzheimer's disease and multiple sclerosis as well as offering a potential target for intervention.

11. Generative artificial intelligence: Opportunities, risks, and responsibilities for oral sciences

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A new perspective article jointly published in the Journal of Dental Research and JADA Foundational Science highlights the transformative potential of generative artificial intelligence (AI) in dental, oral, and craniofacial research while cautioning against its misuse and ethical pitfalls.

12. First drug treatment for sleep apnea may be within reach

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The drug sulthiame reduces the number of breathing pauses and improves sleep quality in patients with obstructive sleep apnea, according to a European clinical study in which the University of Gothenburg played a significant role. The findings offer hope for a drug-based treatment for people who cannot tolerate breathing masks.

13. How fruit flies can help us understand diseases such as ALS

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If we can understand exactly how neurodegenerative diseases such as ALS progress in fruit flies, we may also gain valuable insights into how these diseases develop in humans. Research by neurobiologist Marije Been of Radboud University shows that the formation of certain protein clumps may mark the onset of ALS. She will defend her Ph.D. thesis on this topic on 21 October.

14. Amyotrophic lateral sclerosis and multiple sclerosis likely share an environmental cause, geographic patterns reveal

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A new study published in Scientific Reports indicates that amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) have an extremely high geographic association, even after controlling for race, gender, wealth, latitude, and access to neurological health care.

15. Scientists identify markers of key stem cell populations driving colorectal cancer formation

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Researchers from A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB) have identified markers of two critical stem cell populations that drive colorectal cancer formation.

16. Novel sensor for continuous endoleak monitoring developed

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Endovascular aneurysm repair is a minimally invasive technique for the treatment of abdominal aortic aneurysms—life-threatening bulges in the aorta's abdominal section. However, it carries the risk of recurrence owing to endoleaks after stent graft implantation, necessitating regular follow-up, especially since these leaks cannot be easily linked to specific symptoms.

17. Checkpoint inhibitor promotes tissue repair, offering hope for chronic wound treatment

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Immune checkpoint inhibitors are well known as a form of cancer treatment. Researchers at UZH have now identified a new, important function of these inhibitors: promotion of tissue healing. This finding could help advance the treatment of fibrosis and chronic wounds.

18. Organoids provide new insights into rare malformation of human brain development

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Researchers at the Central Institute of Mental Health (CIMH) in Mannheim, together with international partners, have developed patient-derived brain organoids for the first time in order to better understand the rare genetic disease LIS1-lissencephaly. The study shows how genetic changes disrupt cell structure and protein function and thus cause different disease severities. Initial laboratory results suggest that drugs that are already available could help.

19. New diagnosis code for patients with type 2 diabetes in remission

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Use lifestyle interventions to show no signs of type 2 diabetes for at least three months? There's a code for that: E11.A.

20. Why women's brains face higher risk: Scientists pinpoint X-chromosome gene behind MS and Alzheimer's

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New research by UCLA Health has identified a sex-chromosome linked gene that drives inflammation in the female brain, offering insight into why women are disproportionately affected by conditions such as Alzheimer's disease and multiple sclerosis as well as offering a potential target for intervention.

21. Study finds UK food insecurity is associated with mental health conditions

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Food insecurity affects about one in 13 (7.8%) U.K. households, with higher rates of food insecurity found in Black British households and people with long-term mental health conditions, according to a study published in the open-access journal PLOS One by Maddy Power of the London School of Hygiene and Tropical Medicine, U.K., and colleagues.

22. Challenges seen in diagnosing UTI in children with neurogenic bladder

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Most children with neurogenic bladder (NGB) and diagnosed with febrile urinary tract infection (UTI) in the emergency department (ED) did not meet a commonly recommended definition for UTI, according to a study published online Sept. 15 in the Journal of Pediatric Urology.

23. Child's atopic dermatitis linked to maternal depression scores

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Child atopic dermatitis (AD) is associated with higher maternal depression scores, according to a study published online Oct. 5 in the Journal of the American Academy of Dermatology.

24. Researchers offer tips to turn children's media use into productive screentime

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For better or worse, screentime has become a mainstay in family life—but FIU researchers say boundaries are possible with just a few simple changes.

25. Lidocaine poisoning reports have increased since 2010

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Poisonings and deaths linked to use of local anesthetics decreased over the last decade, but poisonings from lidocaine increased, according to two studies published online recently in Regional Anesthesia & Pain Medicine and the British Journal of Anaesthesia.

26. Project unearths voices from one of the world's first HIV/AIDS service organizations

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Sometimes, you discover history in a garage, stored in dusty boxes, or in memories that go unspoken for decades. Often, it falls to the next generation—curious and respectful—to do the necessary work of sifting, sorting and asking questions.

27. Why do kids want to talk about bums and poos all the time?

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If you spend time around little kids, you may notice one topic seems to be more interesting and hilarious than any other.

28. COVID-19 restrictions linked to decline in immunity to childhood infections

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Scientists have uncovered a link between COVID-19 control measures and a surge in serious infections in children following the pandemic.

29. Brain chemical linked to suicide risk after childhood trauma

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Neuroscientists at Columbia and McGill have discovered that high levels of a brain chemical cause depression and suicidal thoughts in people who experienced trauma or adversity during childhood.

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